4-AMINO-N-(3,5-DICHLORO-PHENYL)-BENZENESULFONAMIDE

Base Information

• Chemical Name: 4-AMINO-N-(3,5-DICHLORO-PHENYL)-BENZENESULFONAMIDE
• CAS No.: 5407-59-0
• Molecular Formula: C12H10Cl2N2O2S
• Molecular Weight: 317.196
• Hs Code.: 2935009090
• Mol file: 5407-59-0.mol

Synonyms:N(1)-(3',5'-Dichlor-phenyl)-sulfanilamid;[(4-aminophenyl)sulfonyl](3,5-dichlorophenyl)amine;4-amino-N-(3,5-dichlorophenyl)-benzenesulfonamide;sulfanilic acid-(3,5-dichloro-anilide);Sulfanilsaeure-(3,5-dichlor-anilid);

Chemical Property of 4-AMINO-N-(3,5-DICHLORO-PHENYL)-BENZENESULFONAMIDE

Chemical Property:

• Vapor Pressure: 1.21E-09mmHg at 25°C
• Melting Point: 150 °C
• Boiling Point: 487.2°C at 760 mmHg
• PKA: 6.60±0.10(Predicted)
• Flash Point: 248.4°C
• PSA: 80.57000
• Density: 1.549g/cm³
• LogP: 5.11140

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-N-(3,5-dichlorophenyl)benzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-AMINO-N-(3,5-DICHLORO-PHENYL)-BENZENESULFONAMIDE

There total 8 articles about 4-AMINO-N-(3,5-DICHLORO-PHENYL)-BENZENESULFONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-nitro-benzenesulfonic acid-(3,5-dichloro-anilide) (296275-16-6) → sulfanilic acid-(3,5-dichloro-anilide) (5407-59-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; under 750.075 Torr;

DOI:10.1016/j.bmc.2008.04.040

Reference yield:

N-acetyl-sulfanilic acid-(3,5-dichloro-anilide) (330468-74-1) → sulfanilic acid-(3,5-dichloro-anilide) (5407-59-0)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01223a015

Reference yield:

p-acetylaminobenzenesulfonyl chloride (121-60-8) → sulfanilic acid-(3,5-dichloro-anilide) (5407-59-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone; pyridine

2: aq. NaOH solution

With pyridine; sodium hydroxide; acetone;

DOI:10.1021/ja01223a015

upstream raw materials:

4-bromo-benzenesulfonic acid-(3,5-dichloro-anilide)

N-acetyl-sulfanilic acid-(3,5-dichloro-anilide)

N-acetyl-sulfanilic acid-(3,5-diamino-anilide)

N-acetyl-sulfanilic acid-(3,5-dinitro-anilide)