2-((2-ethyl(2,6-dimethoxyphenoxy)amino)methyl)1,4-dioxane-(2,3-b)naphthalene

Base Information

Chemical Name:2-((2-ethyl(2,6-dimethoxyphenoxy)amino)methyl)1,4-dioxane-(2,3-b)naphthalene
CAS No.:91677-51-9
Molecular Formula:C₂₃H₂₅NO₅
Molecular Weight:395.455
Hs Code.:
Mol file:91677-51-9.mol

Synonyms:2-((2-ethyl(2,6-dimethoxyphenoxy)amino)methyl)1,4-dioxane-(2,3-b)naphthalene

Suppliers and Price of 2-((2-ethyl(2,6-dimethoxyphenoxy)amino)methyl)1,4-dioxane-(2,3-b)naphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 2-((2-ethyl(2,6-dimethoxyphenoxy)amino)methyl)1,4-dioxane-(2,3-b)naphthalene

Chemical Property:

Vapor Pressure:3.72E-12mmHg at 25°C
Boiling Point:550.2°C at 760 mmHg
Flash Point:231.8°C
PSA：58.18000
Density:1.191g/cm³
LogP:4.05630

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-((2-ethyl(2,6-dimethoxyphenoxy)amino)methyl)1,4-dioxane-(2,3-b)naphthalene

There total 9 articles about 2-((2-ethyl(2,6-dimethoxyphenoxy)amino)methyl)1,4-dioxane-(2,3-b)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 56479-13-1
2-tosyloxymethyl-1,4-dioxane<2,3-b>naphthalene

: 40515-98-8
2-(2,6-dimethoxyphenoxy)ethylamine

: 91677-51-9
2-(<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl)-1,4-dioxane<2,3-b>naphtalene

Guidance literature:: at 105 - 110 ℃; for 20h;

Reference yield: 61.0%

: 753022-32-1
(R)-2-(iodomethyl)-2,3-dihydronaphtho[2,3-b][1,4]dioxine

: 40515-98-8
2-(2,6-dimethoxyphenoxy)ethylamine

: 753023-11-9,91677-51-9
(2S)-2-[((2-(2,6-dimethoxyphenoxy)ethyl)amino)methyl]-2,3-dihydronaphtho[2,3-b][1,4]dioxine

Guidance literature:: In isopropyl alcohol; for 48h; Heating;
DOI:10.1016/j.bmc.2004.06.040

Reference yield:

: 753022-28-5
(R)-3-(3-benzyloxy-2-naphthoxy)-1,2-propanediol

: 753023-11-9,91677-51-9
(2S)-2-[((2-(2,6-dimethoxyphenoxy)ethyl)amino)methyl]-2,3-dihydronaphtho[2,3-b][1,4]dioxine

Guidance literature:: Multi-step reaction with 5 steps

1: 74 percent / pyridine / 20 h / 20 °C

2: 53 percent / H₂ / Pd/C / ethyl acetate; methanol / 3 h / 20 °C

3: 99 percent / K₂CO₃ / acetone / 5 h / Heating

4: 91 percent / NaI / acetone / 18 h / Heating

5: 61 percent / propan-2-ol / 48 h / Heating

With pyridine; hydrogen; potassium carbonate; sodium iodide; palladium on activated charcoal; In methanol; ethyl acetate; isopropyl alcohol; acetone;
DOI:10.1016/j.bmc.2004.06.040