6-bromo-2H-1,3-benzodioxol-4-amine

Base Information

Chemical Name:6-bromo-2H-1,3-benzodioxol-4-amine
CAS No.:492444-10-7
Molecular Formula:C₇H₆BrNO₂
Molecular Weight:216.034
Hs Code.:
European Community (EC) Number:839-259-7
Mol file:492444-10-7.mol

Synonyms:6-bromo-2H-1,3-benzodioxol-4-amine;492444-10-7;6-bromo-1,3-benzodioxol-4-amine;SCHEMBL1171844;TYSVFBOLGCFLGI-UHFFFAOYSA-N;6-bromo-1,3-dioxaindan-4-amine;6-bromobenzo[1,3]dioxol-4-amine;AKOS034120198;DB-107945;EN300-814497;Z1509409772

Suppliers and Price of 6-bromo-2H-1,3-benzodioxol-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
6-Bromo-2H-1,3-benzodioxol-4-amine
2.5g
$ 2102.00

AK Scientific
6-Bromo-2H-1,3-benzodioxol-4-amine
250mg
$ 604.00

Total 2 raw suppliers

Chemical Property of 6-bromo-2H-1,3-benzodioxol-4-amine

Chemical Property:

Boiling Point:308.7±42.0 °C(Predicted)
PSA：44.48000
Density:1.814±0.06 g/cm3(Predicted)
LogP:2.34120
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:214.95819
Heavy Atom Count:11
Complexity:155

Purity/Quality:

95% ^*data from raw suppliers

6-Bromo-2H-1,3-benzodioxol-4-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1OC2=CC(=CC(=C2O1)N)Br

Technology Process of 6-bromo-2H-1,3-benzodioxol-4-amine

There total 1 articles about 6-bromo-2H-1,3-benzodioxol-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 492444-11-8
tert-butyl N-(6-bromo-1,3-benzodioxol-4-yl)carbamate

: 492444-10-7
5-bromo-2,3-methylenedioxyaniline

Guidance literature:: tert-butyl N-(6-bromo-1,3-benzodioxol-4-yl)carbamate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

With sodium hydrogencarbonate; In tert-butyl methyl ether; water;

Reference yield:

: 492444-10-7
5-bromo-2,3-methylenedioxyaniline

: 945395-47-1
7-[(2-{[3-(Methylsulfonyl)phenyl]amino}pyrimidin-4-yl)amino]-1,3-benzodioxole-5-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine; zinc; 1,1'-bis-(diphenylphosphino)ferrocene / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / N,N-dimethyl-formamide / 110 °C

2: sodium hydride / N,N-dimethyl acetamide; mineral oil / 17 - 25 °C

3: hydrogenchloride / isopropyl alcohol; 1,4-dioxane / 0.33 h / 110 °C / Microwave irradiation

With hydrogenchloride; 1,1'-bis-(diphenylphosphino)ferrocene; sodium hydride; N-ethyl-N,N-diisopropylamine; zinc; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; N,N-dimethyl acetamide; N,N-dimethyl-formamide; isopropyl alcohol; mineral oil;