2H-Pyran-2,6(3H)-dione, 4-(4-fluorophenyl)dihydro-

Base Information

Chemical Name:2H-Pyran-2,6(3H)-dione, 4-(4-fluorophenyl)dihydro-
CAS No.:4926-12-9
Molecular Formula:C11H9FO3
Molecular Weight:208.189
Hs Code.:

Synonyms:3-(4-fluoro)-phenylglutaric acid anhydride;4-(4-Fluoro-phenyl)-dihydro-pyran-2,6-dione;3-(4-fluoro-phenyl)-pentanedioic acid anhydride;4-(4-fluorophenyl)dihydropyran-2,6-dione;3-(4-fluorophenyl)-glutaric acid anhydride;3-(4-fluorophenyl)glutaric anhydride;4-(4-fluorophenyl)glutaric anhydride;

Suppliers and Price of 2H-Pyran-2,6(3H)-dione, 4-(4-fluorophenyl)dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of 2H-Pyran-2,6(3H)-dione, 4-(4-fluorophenyl)dihydro-

Chemical Property:

Melting Point:84 - 86 °C (Petroleum ether)
PSA：43.37000
LogP:1.77290

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2H-Pyran-2,6(3H)-dione, 4-(4-fluorophenyl)dihydro-

There total 12 articles about 2H-Pyran-2,6(3H)-dione, 4-(4-fluorophenyl)dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 3449-63-6
3-(4-fluorophenyl)pentan-1,5-dioic acid

: 4926-12-9
4-(4-fluorophenyl)dihydropyran-2,6(3H)-dione

Guidance literature:: With acetyl chloride; at 65 ℃;
DOI:10.1021/ja067777y

Reference yield:

: 459-57-4
4-fluorobenzaldehyde

: 4926-12-9
4-(4-fluorophenyl)dihydropyran-2,6(3H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: piperidine / 72 h / 20 °C

1.2: aq. KOH / 3 h / 80 - 95 °C

2.1: AcCl / 3 h

With piperidine; acetyl chloride;
DOI:10.1016/j.tetasy.2005.06.025

Reference yield:

: 459-57-4
4-fluorobenzaldehyde

: 4926-12-9
4-(4-fluorophenyl)dihydropyran-2,6(3H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1: piperidine / 72 h / 20 °C

2: 3.66 g / KOH / H₂O / 3 h / 80 °C

3: 55 percent / Ac₂O / 130 °C

With piperidine; potassium hydroxide; acetic anhydride; In water;
DOI:10.1021/jm0004953