(E)-2,3-Dihydro-3-((4-chlorophenyl)methylene)-4H-1-benzopyran-4-one

Base Information

Chemical Name:(E)-2,3-Dihydro-3-((4-chlorophenyl)methylene)-4H-1-benzopyran-4-one
CAS No.:62174-08-7
Molecular Formula:C₁₆H₁₁ClO₂
Molecular Weight:270.715
Hs Code.:
DSSTox Substance ID:DTXSID501159158
Nikkaji Number:J601.129B,J601.134I,J938.664E
Wikidata:Q76145778
Pharos Ligand ID:5MHGRVXZ8KNL
ChEMBL ID:CHEMBL452004

Synonyms:62174-08-7;(E)-2,3-Dihydro-3-((4-chlorophenyl)methylene)-4H-1-benzopyran-4-one;(E)-3-(4-chlorobenzylidene)chroman-4-one;3-(4-Chlorobenzylidene)chroman-4-one;(3E)-3-[(4-chlorophenyl)methylidene]chromen-4-one;CHEMBL452004;(3E)-3-[(4-chlorophenyl)methylidene]-3,4-dihydro-2H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-3-((4-chlorophenyl)methylene)-, (E)-;61661-20-9;3-[(E)-(4-chlorophenyl)methylidene]-2,3-dihydro-4H-chromen-4-one;DTXSID501159158;BDBM50341675;MFCD00205466;AKOS001120940;CCG-248035;LS-39542;3-[(Z)-4-Chlorobenzylidene]chroman-4-one;(e)-3-(4'-chlorobenzylidene)-4-chromanone;(3E)-3-[(4-chlorophenyl)methylene]chroman-4-one;2W-0607;3-(4-chlorobenzylidene)-2,3-dihydrochromen-4-one;3-(4-Chlorobenzylidene)-2,3-dihydro-1-benzopyran-4-one;(3E)-3-[(4-Chlorophenyl)methylene]-2,3-dihydro-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 3-[(4-chlorophenyl)methylene]-2,3-dihydro-, (3E)-

Suppliers and Price of (E)-2,3-Dihydro-3-((4-chlorophenyl)methylene)-4H-1-benzopyran-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-[(E)-(4-Chlorophenyl)methylidene]-2,3-dihydro-4H-chromen-4-one
5g
$ 7343.00

Matrix Scientific
3-[(E)-(4-Chlorophenyl)methylidene]-2,3-dihydro-4H-chromen-4-one
1g
$ 1836.00

Matrix Scientific
3-[(E)-(4-Chlorophenyl)methylidene]-2,3-dihydro-4H-chromen-4-one
500mg
$ 918.00

American Custom Chemicals Corporation
(E)-3-(4-CHLOROBENZYLIDENE)-2,3-DIHYDROCHROMEN-4-ONE 95.00%
1MG
$ 586.97

Total 4 raw suppliers

Chemical Property of (E)-2,3-Dihydro-3-((4-chlorophenyl)methylene)-4H-1-benzopyran-4-one

Chemical Property:

Vapor Pressure:3.53E-08mmHg at 25°C
Boiling Point:446.8°C at 760 mmHg
Flash Point:186.8°C
PSA：26.30000
Density:1.33g/cm³
LogP:3.99870
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:270.0447573
Heavy Atom Count:19
Complexity:369

Purity/Quality:

99% ^*data from raw suppliers

3-[(E)-(4-Chlorophenyl)methylidene]-2,3-dihydro-4H-chromen-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(=CC2=CC=C(C=C2)Cl)C(=O)C3=CC=CC=C3O1
Isomeric SMILES:C1/C(=C\C2=CC=C(C=C2)Cl)/C(=O)C3=CC=CC=C3O1

Technology Process of (E)-2,3-Dihydro-3-((4-chlorophenyl)methylene)-4H-1-benzopyran-4-one

There total 9 articles about (E)-2,3-Dihydro-3-((4-chlorophenyl)methylene)-4H-1-benzopyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 491-37-2
2,3-dihydro-4H-1-benzopyran-4-one

: 104-88-1
4-chlorobenzaldehyde

: 61661-20-9,61926-52-1,62174-08-7
(E)-3-(4-chloro-benzylidene)-chroman-4-one

Guidance literature:: With sulfuric acid; In acetic acid; at 20 ℃; for 0.333333h;

Reference yield: 85.0%

: (3R*,αS*)-3-bromo-3-(α-bromo-4-chlorobenzyl)chromanone

: 61661-20-9,61926-52-1,62174-08-7
(E)-3-(4-chloro-benzylidene)-chroman-4-one

: 3-(α-azido-4-chlorobenzyl)chromone

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1016/S0040-4020(01)00142-9

Reference yield: 59.0%

: 533-58-4
2-Iodophenol

: 103979-29-9,1794-54-3
para-chlorocinnamyl chloride

: benzene-1,3,5-triyl triformate

: 61661-20-9,61926-52-1,62174-08-7
(E)-3-(4-chloro-benzylidene)-chroman-4-one

Guidance literature:: With potassium phosphate; palladium diacetate; triethylamine; catacxium A; In 1,4-dioxane; at 90 ℃; for 25h; Inert atmosphere; Sealed tube;
DOI:10.1002/chem.201900015