3,8-dimethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-2,9-diol

Base Information

Chemical Name:3,8-dimethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-2,9-diol
CAS No.:29944-24-9
Molecular Formula:C₁₉H₂₁NO₄
Molecular Weight:327.38
Hs Code.:
Mol file:29944-24-9.mol

Synonyms:Argemonine,O2,O9-didemethyl-, (?à)- (8CI); Dibenzo[a,e]cycloocten-5,11-imine-2,9-diol,5,6,11,12-tetrahydro-3,8-dimethoxy-13-methyl- (9CI);Dibenzo[a,e]cycloocten-5,11-imine-2,9-diol,5,6,11,12-tetrahydro-3,8-dimethoxy-13-methyl-, (?à)-; (?à)-Bisnorargemonine; (?à)-Rotundine; NSC 148825

Suppliers and Price of 3,8-dimethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-2,9-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 3,8-dimethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-2,9-diol

Chemical Property:

Vapor Pressure:7.96E-10mmHg at 25°C
Boiling Point:479.7°C at 760 mmHg
Flash Point:243.9°C
Density:1.277g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3,8-dimethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-2,9-diol

There total 5 articles about 3,8-dimethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-2,9-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72258-92-5
(+/-)-N-Formyl-N-norreticuline

: 29944-24-9
Bisnorargemonin

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) / 1.5 h / -78 °C

2: 87 percent / 1 h / 200 - 210 °C / 200 Torr

3: 75 percent / CH₃SO₃H / acetonitrile / 6.5 h / 25 °C

4: 1.) BH₃; 2.) HCl / 1.) THF, reflux; 2.) HCl, CH₃OH, reflux, 4 h.

With hydrogenchloride; methanesulfonic acid; borane; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In acetonitrile;
DOI:10.1021/jo01292a009

Reference yield:

: 72258-99-2
(+/-)-3,4-dehydro-N-formyl-N-norreticuline

: 29944-24-9
Bisnorargemonin

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / CH₃SO₃H / acetonitrile / 6.5 h / 25 °C

2: 1.) BH₃; 2.) HCl / 1.) THF, reflux; 2.) HCl, CH₃OH, reflux, 4 h.

With hydrogenchloride; methanesulfonic acid; borane; In acetonitrile;
DOI:10.1021/jo01292a009

Reference yield:

: 72258-98-1
(+/-)-4-Methoxy-N-formyl-N-norreticuline

: 29944-24-9
Bisnorargemonin

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / 1 h / 200 - 210 °C / 200 Torr

2: 75 percent / CH₃SO₃H / acetonitrile / 6.5 h / 25 °C

3: 1.) BH₃; 2.) HCl / 1.) THF, reflux; 2.) HCl, CH₃OH, reflux, 4 h.

With hydrogenchloride; methanesulfonic acid; borane; In acetonitrile;
DOI:10.1021/jo01292a009