1-Butyl-3-(pyridine-4-carbonylamino)thiourea

Base Information

Chemical Name:1-Butyl-3-(pyridine-4-carbonylamino)thiourea
CAS No.:74270-74-9
Molecular Formula:C₁₁H₁₆N₄OS
Molecular Weight:252.34
Hs Code.:
NSC Number:201741
DSSTox Substance ID:DTXSID10364367
Nikkaji Number:J702.679J
ChEMBL ID:CHEMBL1461695

Synonyms:abouthiouzine

Suppliers and Price of 1-Butyl-3-(pyridine-4-carbonylamino)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-Butyl-3-(pyridine-4-carbonylamino)thiourea

Chemical Property:

Density:1.192g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:252.10448232
Heavy Atom Count:17
Complexity:254

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCNC(=S)NNC(=O)C1=CC=NC=C1

Technology Process of 1-Butyl-3-(pyridine-4-carbonylamino)thiourea

There total 2 articles about 1-Butyl-3-(pyridine-4-carbonylamino)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 54-85-3,7640-37-1
isoniazid

: 592-82-5
butyl isothiocyanate

: 74270-74-9
1-n-butyl-3-(isonicotinamido)-2-thiourea

Guidance literature:: In benzene; Heating;
DOI:10.1023/A:1016049921842

Reference yield:

: 74270-74-9
1-n-butyl-3-(isonicotinamido)-2-thiourea

Guidance literature:: Hydrazid I, Dithiomethan;

Reference yield:

: 74270-74-9
1-n-butyl-3-(isonicotinamido)-2-thiourea

: 1412407-25-0
C₂₂H₂₇N₅OS

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / water / 16 h / Reflux

2: caesium carbonate / acetonitrile / 16 h

With potassium carbonate; caesium carbonate; In water; acetonitrile;
DOI:10.1016/j.bmcl.2014.04.081