(R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid

Base Information

Chemical Name:(R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid
CAS No.:496930-10-0
Molecular Formula:C11H11BrN2O2
Molecular Weight:283.12100
Hs Code.:2933998090
DSSTox Substance ID:DTXSID50463505
Nikkaji Number:J1.796.454B
Mol file:496930-10-0.mol

Synonyms:496930-10-0;(R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid;6-BROMO-D-TRYPTOPHAN;(2R)-2-AMINO-3-(6-BROMO-1H-INDOL-3-YL)PROPANOIC ACID;(R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoicacid;SCHEMBL8502601;DTXSID50463505;MFCD17214434;AKOS016008212;AS-82889;CS-0327153;6-Bromo-D-tryptophan (H-D-Trp(6-Br)-OH)

Suppliers and Price of (R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoicacid 95+%
1g
$ 589.00

Apolloscientific
6-Bromo-D-tryptophan 97%
250mg
$ 301.00

Apolloscientific
6-Bromo-D-tryptophan 97%
500mg
$ 450.00

Apolloscientific
6-Bromo-D-tryptophan 97%
1g
$ 675.00

American Custom Chemicals Corporation
D-TRYPTOPHAN, 6-BROMO- 95.00%
0.25G
$ 633.00

American Custom Chemicals Corporation
D-TRYPTOPHAN, 6-BROMO- 95.00%
5MG
$ 504.98

Alichem
(R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoicacid
1g
$ 1166.30

Alichem
(R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoicacid
250mg
$ 449.08

Activate Scientific
6-Bromo-D-tryptophan 95% ee
1 g
$ 523.00

Acrotein
6-Bromo-D-tryptophan 97%
0.25g
$ 183.33

Total 15 raw suppliers

Chemical Property of (R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid

Chemical Property:

PSA：79.11000
LogP:2.58510
Storage Temp.:2-8°C
XLogP3:-0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:282.00039
Heavy Atom Count:16
Complexity:275

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1Br)NC=C2CC(C(=O)O)N
Isomeric SMILES:C1=CC2=C(C=C1Br)NC=C2C[C@H](C(=O)O)N

Technology Process of (R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid

There total 9 articles about (R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 153-94-6,27732-43-0,80206-30-0,27813-82-7
D-tryptophan

: 496930-10-0
6'-bromo-D-tryptophan

Guidance literature:: With oxygen; FAD-dependent tryptophan halogenase Thal; sodium bromide; In isopropyl alcohol; at 25 ℃; pH=7.4; chemoselective reaction; Enzymatic reaction;
DOI:10.1021/acs.jmedchem.0c01536

Reference yield: 94.0%

: (R)-6-bromo-N-(tert-butoxycarbonyl)tryptophan methyl ester

: 496930-10-0
6'-bromo-D-tryptophan

Guidance literature:: With water; silica gel; at 140 ℃; for 20h; enantioselective reaction;
DOI:10.1016/j.tetlet.2020.151923

Reference yield: 37.7%

: 85515-06-6
N^α-acetyl-6-bromo-D,L-tryptophan

: 496930-10-0
6'-bromo-D-tryptophan

: 496930-11-1
N^α-acetyl-6-bromo-L-tryptophan

Guidance literature:: With D-aminoacylase; cobalt(II) chloride; In phosphate buffer; at 37 ℃; for 23h; pH=7.41;
DOI:10.1016/S0040-4020(02)00909-2