Technology Process of 1H-Imidazole-4-propanal, b-methyl-1-(triphenylmethyl)-
There total 4 articles about 1H-Imidazole-4-propanal, b-methyl-1-(triphenylmethyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 1.75h;
DOI:10.1016/j.bmc.2004.02.007
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran / 1 h
1.2: 91 percent / tetrahydrofuran / 18 h / Heating
2.1: H2 / Pd/C / tetrahydrofuran; ethyl acetate / 4 h / 20 °C
2.2: 80 percent / triethylamine / dimethylformamide / 96 h / 20 °C
3.1: 80 percent / diisobutylaluminum hydride / tetrahydrofuran; hexane / 1.75 h / -78 °C
With
hydrogen; sodium hydride; diisobutylaluminium hydride;
palladium on activated charcoal;
In
tetrahydrofuran; hexane; ethyl acetate;
1.2: Horner-Emmons olefination;
DOI:10.1016/j.bmc.2004.02.007
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 98 percent / tetrahydrofuran; diethyl ether / 1 h
2.1: 85 percent / manganese(IV) oxide / CH2Cl2 / 12 h / 20 °C
3.1: sodium hydride / tetrahydrofuran / 1 h
3.2: 91 percent / tetrahydrofuran / 18 h / Heating
4.1: H2 / Pd/C / tetrahydrofuran; ethyl acetate / 4 h / 20 °C
4.2: 80 percent / triethylamine / dimethylformamide / 96 h / 20 °C
5.1: 80 percent / diisobutylaluminum hydride / tetrahydrofuran; hexane / 1.75 h / -78 °C
With
manganese(IV) oxide; hydrogen; sodium hydride; diisobutylaluminium hydride;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane; ethyl acetate;
1.1: Grignard reaction / 3.2: Horner-Emmons olefination;
DOI:10.1016/j.bmc.2004.02.007
