2-Amino-2-(3-chlorophenyl)acetonitrile hydrochloride

Base Information

Chemical Name:2-Amino-2-(3-chlorophenyl)acetonitrile hydrochloride
CAS No.:49704-72-5
Molecular Formula:C8H7ClN2.ClH
Molecular Weight:203.071
Hs Code.:

Synonyms:2-amino-2-(3-chlorophenyl)acetonitrile hydrochloride;49704-72-5;2-amino-2-(3-chlorophenyl)acetonitrile;hydrochloride;amino(3-chlorophenyl)acetonitrile hydrochloride;SCHEMBL5685261;EN300-39244;G26000;2-amino-2-(3-chlorophenyl)acetonitrilehydrochloride;Z398556966

Suppliers and Price of 2-Amino-2-(3-chlorophenyl)acetonitrile hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-amino-2-(3-chlorophenyl)acetonitrilehydrochloride
25mg
$ 45.00

AK Scientific
2-Amino-2-(3-chlorophenyl)acetonitrilehydrochloride
2.5g
$ 777.00

Total 4 raw suppliers

Chemical Property of 2-Amino-2-(3-chlorophenyl)acetonitrile hydrochloride

Chemical Property:

Melting Point:175 - 176 °C
PSA：49.81000
LogP:3.36568
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:202.0064537
Heavy Atom Count:12
Complexity:172

Purity/Quality:

95% ^*data from raw suppliers

2-amino-2-(3-chlorophenyl)acetonitrilehydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Cl)C(C#N)N.Cl

Technology Process of 2-Amino-2-(3-chlorophenyl)acetonitrile hydrochloride

There total 4 articles about 2-Amino-2-(3-chlorophenyl)acetonitrile hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100948-25-2,82128-87-8
2-(3-chlorophenyl)-2-(trimethylsilyloxy)acetonitrile

: 49704-72-5
α-amino-(3-chlorophenyl)acetonitrile hydrochloride

Guidance literature:: With ammonia; In methanol; at 40 ℃; for 2h; Yield given;
DOI:10.1016/S0040-4039(01)91205-5

Reference yield:

: 93554-79-1
alpha-amino-(3-chlorophenyl)acetonitrile

: 49704-72-5
α-amino-(3-chlorophenyl)acetonitrile hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; at 20 ℃; for 0.25h; Inert atmosphere;
DOI:10.1039/c6cc04308a

Reference yield:

: 587-04-2
m-Chlorobenzaldehyde

: 49704-72-5
α-amino-(3-chlorophenyl)acetonitrile hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: zinc iodide / neat (no solvent) / 0.25 h

2: ammonia / methanol / 2 h / 40 °C

With ammonia; zinc(II) iodide; In methanol;
DOI:10.1016/S0040-4039(01)91205-5