3-Iodoquinolin-8-amine

Base Information

Chemical Name:3-Iodoquinolin-8-amine
CAS No.:497084-47-6
Molecular Formula:C9H7IN2
Molecular Weight:270.07000
Hs Code.:2933499090
European Community (EC) Number:939-084-7
DSSTox Substance ID:DTXSID401313282
Mol file:497084-47-6.mol

Synonyms:3-iodoquinolin-8-amine;497084-47-6;8-amino-3-iodoquinoline;MFCD09907947;8-Quinolinamine, 3-iodo-;3-Iodo-8-aMinoquinoline;3-iodo-quinolin-8-ylamine;DTXSID401313282;AMY32333;XUA08447;AKOS015996880;GG-0221;SB70120;SY281362;CS-0312084

Suppliers and Price of 3-Iodoquinolin-8-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3-Iodoquinolin-8-amine
1 g
$ 343.00

SynQuest Laboratories
3-Iodoquinolin-8-amine
500 mg
$ 256.00

Matrix Scientific
3-Iodoquinolin-8-amine >97%
1g
$ 487.00

Matrix Scientific
3-Iodoquinolin-8-amine >97%
500mg
$ 390.00

Crysdot
3-Iodoquinolin-8-amine 95+%
1g
$ 650.00

Crysdot
3-Iodoquinolin-8-amine 95+%
25mg
$ 90.00

Crysdot
3-Iodoquinolin-8-amine 95+%
250mg
$ 385.00

Chemenu
3-Iodoquinolin-8-amine 95%
1g
$ 433.00

American Custom Chemicals Corporation
3-IODOQUINOLIN-8-AMINE 95.00%
5MG
$ 499.70

Alichem
3-Iodoquinolin-8-amine
250mg
$ 280.16

Total 11 raw suppliers

Chemical Property of 3-Iodoquinolin-8-amine

Chemical Property:

PSA：38.91000
LogP:3.00280
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:269.96540
Heavy Atom Count:12
Complexity:163

Purity/Quality:

97% ^*data from raw suppliers

3-Iodoquinolin-8-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=CC(=CN=C2C(=C1)N)I

Technology Process of 3-Iodoquinolin-8-amine

There total 3 articles about 3-Iodoquinolin-8-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 497084-46-5
3-iodo-8-nitroquinoline

: 497084-47-6
8-amino-3-iodoquinoline

Guidance literature:: With hydrogenchloride; iron; In ethanol; for 3h; Heating;
DOI:10.1007/s00706-002-0495-6

Reference yield:

: 607-35-2
8-nitroquinoline

: 497084-47-6
8-amino-3-iodoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / N-iodosuccinimide / acetic acid / Heating

2: 93 percent / Fe powder; HCl / ethanol / 3 h / Heating

With hydrogenchloride; N-iodo-succinimide; iron; In ethanol; acetic acid;
DOI:10.1007/s00706-002-0495-6

Reference yield:

: 88-74-4
2-nitro-aniline

: 497084-47-6
8-amino-3-iodoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium iodide / 0.08 h / 20 °C

1.2: 0.17 h / Cooling with ice

1.3: 2 h / 140 °C

2.1: iodine; tert.-butylhydroperoxide / acetonitrile; water / 24 h / 80 °C

3.1: pyrographite; hydrazine hydrate / methanol / 12 h / 80 °C

With tert.-butylhydroperoxide; iodine; pyrographite; hydrazine hydrate; sodium iodide; In methanol; water; acetonitrile;
DOI:10.1021/acs.joc.9b00942