4,5-DIAMINO-2-CHLOROBENZONITRILE

Base Information

Chemical Name:4,5-DIAMINO-2-CHLOROBENZONITRILE
CAS No.:497147-90-7
Molecular Formula:C₇H₆ClN₃
Molecular Weight:167.598
Hs Code.:
Mol file:497147-90-7.mol

Synonyms:

Suppliers and Price of 4,5-DIAMINO-2-CHLOROBENZONITRILE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,5-Diamino-2-chlorobenzonitrileDihydrochloride
2.5g
$ 1320.00

Chemcia Scientific
4,5-Diamino-2-chloro-benzonitrile 95%
1 G
$ 565.00

AK Scientific
4,5-DIAMINO-2-CHLOROBENZONITRILE
250mg
$ 345.20

Total 3 raw suppliers

Chemical Property of 4,5-DIAMINO-2-CHLOROBENZONITRILE

Chemical Property:

Boiling Point:420.5±45.0 °C(Predicted)
PKA:1.72±0.10(Predicted)
PSA：75.83000
Density:1.41±0.1 g/cm3(Predicted)
LogP:2.53848

Purity/Quality:

99% ^*data from raw suppliers

4,5-Diamino-2-chlorobenzonitrileDihydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4,5-Diamino-2-chlorobenzonitrile Dihydrochloride, can be used in the development of 2-(2-hydroxy-3-ethoxyphenyl)-1H-benzimidazole-5-carboxamidine, as potent and selective urokinase-type plasminogen activator inhibitors.

Technology Process of 4,5-DIAMINO-2-CHLOROBENZONITRILE

There total 4 articles about 4,5-DIAMINO-2-CHLOROBENZONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 172455-36-6
2-chloro-4-amino-5-nitrobenzonitrile

: 497147-90-7
2-chloro-4,5-diaminobenzonitrile

Guidance literature:: With hydrogen; palladium on activated charcoal; under 760 Torr;
DOI:10.1016/S0960-894X(02)00311-6

Reference yield:

: 60702-69-4
2-chloro-4-fluorobenzonitrile

: 497147-90-7
2-chloro-4,5-diaminobenzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: potassium nitrate; 18 N sulfuric acid

2: ammonium hydroxide

3: H₂ / Pd/C / 760 Torr

With ammonium hydroxide; sulfuric acid; hydrogen; potassium nitrate; palladium on activated charcoal;
DOI:10.1016/S0960-894X(02)00311-6

Reference yield:

: 183325-39-5
2-chloro-4-fluoro-5-nitrobenzonitrile

: 497147-90-7
2-chloro-4,5-diaminobenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium hydroxide

2: H₂ / Pd/C / 760 Torr

With ammonium hydroxide; hydrogen; palladium on activated charcoal;
DOI:10.1016/S0960-894X(02)00311-6