Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-methoxy-

Base Information

Chemical Name:Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-methoxy-
CAS No.:81257-95-6
Molecular Formula:C₁₂H₁₃NO₂
Molecular Weight:203.241
Hs Code.:
DSSTox Substance ID:DTXSID10230997
Wikidata:Q83111799
Mol file:81257-95-6.mol

Synonyms:81257-95-6;Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-methoxy-;1,7,8,9-Tetrahydro-5-methoxypyrano(2,3-g)indole;5-Methoxy-7,8,9-trihydro-pyranno(2,3-g)indole [French];5-Methoxy-7,8,9-trihydro-pyranno(2,3-g)indole;SCHEMBL10747138;DTXSID10230997;LS-127390

Suppliers and Price of Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-methoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,7,8,9-TETRAHYDRO-5-METHOXYPYRANO(2,3-G)INDOLE 95.00%
5MG
$ 502.77

Total 3 raw suppliers

Chemical Property of Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-methoxy-

Chemical Property:

Vapor Pressure:3.65E-06mmHg at 25°C
Boiling Point:397.4°C at 760 mmHg
Flash Point:144.1°C
PSA：34.25000
Density:1.241g/cm³
LogP:2.50150
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:203.094628657
Heavy Atom Count:15
Complexity:234

Purity/Quality:: 1,7,8,9-TETRAHYDRO-5-METHOXYPYRANO(2,3-G)INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C2C(=C3C(=C1)C=CN3)CCCO2

Technology Process of Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-methoxy-

There total 6 articles about Pyrano(2,3-g)indole, 1,7,8,9-tetrahydro-5-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 81257-92-3
acide methoxy-5 tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

: 81257-95-6
5-methoxy-1,7,8,9-tetrahydropyrano<2,3-g>indole

Guidance literature:: With chromium(III) oxide; copper(II) oxide; In quinoline; at 190 - 195 ℃; for 4h;
DOI:10.1139/v82-298

Reference yield:

: 81258-21-1
bromo-6 methoxy-8 chromanne

: 81257-95-6
5-methoxy-1,7,8,9-tetrahydropyrano<2,3-g>indole

Guidance literature:: Multi-step reaction with 5 steps

1: 1) n-butyllithium / 1) ether, -50 deg C, 6 h; 2) ether, -50 deg C, 12 h

2: Na / methanol / 6 h / 0 °C

3: 38 percent / N₂ / xylene / 5 h / Heating

4: 98 percent / 1) KOH, H₂O; 2) 5 N HCl / 1) reflux, 1.5 h, MeOH; 2) 0 deg C, MeOH

5: 60 percent / CuO, Cr₂O₃ / quinoline / 4 h / 190 - 195 °C

With hydrogenchloride; chromium(III) oxide; potassium hydroxide; n-butyllithium; nitrogen; water; sodium; copper(II) oxide; In quinoline; methanol; xylene;
DOI:10.1139/v82-298

Reference yield:

: 81258-23-3
methoxy-8 dihydro-3,4 2H-benzopyranne-1 carbaldehyde-6

: 81257-95-6
5-methoxy-1,7,8,9-tetrahydropyrano<2,3-g>indole

Guidance literature:: Multi-step reaction with 4 steps

1: Na / methanol / 6 h / 0 °C

2: 38 percent / N₂ / xylene / 5 h / Heating

3: 98 percent / 1) KOH, H₂O; 2) 5 N HCl / 1) reflux, 1.5 h, MeOH; 2) 0 deg C, MeOH

4: 60 percent / CuO, Cr₂O₃ / quinoline / 4 h / 190 - 195 °C

With hydrogenchloride; chromium(III) oxide; potassium hydroxide; nitrogen; water; sodium; copper(II) oxide; In quinoline; methanol; xylene;
DOI:10.1139/v82-298