2-Propen-1-ol, 2-((1-(6-amino-9H-purin-9-yl)ethenyl)oxy)-

Base Information

Chemical Name:2-Propen-1-ol, 2-((1-(6-amino-9H-purin-9-yl)ethenyl)oxy)-
CAS No.:104532-19-6
Molecular Formula:C₁₀H₁₁N₅O₂
Molecular Weight:233.23
Hs Code.:
ChEMBL ID:CHEMBL83033
DSSTox Substance ID:DTXSID00146538
Nikkaji Number:J687.570J
Wikidata:Q83011370

Synonyms:104532-19-6;2-Propen-1-ol, 2-((1-(6-amino-9H-purin-9-yl)ethenyl)oxy)-;2-Propen-1-ol, 2-[[1-(6-amino-9H-purin-9-yl)ethenyl]oxy]-;CHEMBL83033;DTXSID00146538;2-[1-(6-aminopurin-9-yl)vinyloxy]prop-2-en-1-ol

Suppliers and Price of 2-Propen-1-ol, 2-((1-(6-amino-9H-purin-9-yl)ethenyl)oxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Propen-1-ol, 2-((1-(6-amino-9H-purin-9-yl)ethenyl)oxy)-

Chemical Property:

Vapor Pressure:7.09E-12mmHg at 25°C
Boiling Point:525.6°C at 760 mmHg
Flash Point:271.7°C
Density:1.45g/cm³
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:233.09127461
Heavy Atom Count:17
Complexity:322

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=C(CO)OC(=C)N1C=NC2=C(N=CN=C21)N

Technology Process of 2-Propen-1-ol, 2-((1-(6-amino-9H-purin-9-yl)ethenyl)oxy)-

There total 9 articles about 2-Propen-1-ol, 2-((1-(6-amino-9H-purin-9-yl)ethenyl)oxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 104532-18-5
5'-O-(tert-butyldimethylsilyl)-2',3'-dideoxy-2',3'-secoadenosine-1',3'-diene

: 104532-19-6
2',3'-Dideoxy-2',3'-secoadenosin-1',2'-diene

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 0.333333h; Ambient temperature;
DOI:10.1021/jm00162a005

Reference yield: 71.0%

: 173202-62-5
2',3'-Dideoxy-5'-O,N₆-bis(triphenylmethyl)-2',3'-secoadenosine-1',3'-diene

: 104532-19-6
2',3'-Dideoxy-2',3'-secoadenosin-1',2'-diene

Guidance literature:: With zinc dibromide; In dichloromethane; for 18h; Ambient temperature;
DOI:10.1002/hlca.19950780714

Reference yield:

: 18048-85-6
5'-O-(triphenylmethyl)adenosine

: 104532-19-6
2',3'-Dideoxy-2',3'-secoadenosin-1',2'-diene

Guidance literature:: Multi-step reaction with 7 steps

1: 9.9 g / sodium periodate / methanol; H₂O / 20 h / Ambient temperature

2: 87 percent / NaBH₄ / ethanol / 2 h / Ambient temperature

3: 77 percent / pyridine / 24 h / Ambient temperature

4: 73 percent / 80percent acetic acid / 6 h / 65 °C

5: 93 percent / imidazole / dimethylformamide / 3.5 h / Ambient temperature

6: 59 percent / t-BuOK / 2-methyl-propan-2-ol / 2.5 h / 60 °C

7: 79 percent / tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / Ambient temperature

With pyridine; 1H-imidazole; sodium tetrahydroborate; sodium periodate; potassium tert-butylate; tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; methanol; ethanol; water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1021/jm00162a005