(1R,2R)-1-(3,4-Dimethoxyphenyl)propane-1,2,3-triol

Base Information

Chemical Name:(1R,2R)-1-(3,4-Dimethoxyphenyl)propane-1,2,3-triol
CAS No.:499135-15-8
Molecular Formula:C11H16O5
Molecular Weight:228.245
Hs Code.:
DSSTox Substance ID:DTXSID70453064
Nikkaji Number:J1.816.455H
Wikidata:Q82274047
Metabolomics Workbench ID:126123
ChEMBL ID:CHEMBL2011543

Synonyms:(1R,2R)-1-(3,4-Dimethoxyphenyl)propane-1,2,3-triol;CHEMBL2011543;499135-15-8;DTXSID70453064;BDBM50379796

Suppliers and Price of (1R,2R)-1-(3,4-Dimethoxyphenyl)propane-1,2,3-triol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1R,2R)-1-(3,4-Dimethoxyphenyl)propane-1,2,3-triol

Chemical Property:

XLogP3:-0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:228.09977361
Heavy Atom Count:16
Complexity:199

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(C(CO)O)O)OC
Isomeric SMILES:COC1=C(C=C(C=C1)[C@H]([C@@H](CO)O)O)OC

Technology Process of (1R,2R)-1-(3,4-Dimethoxyphenyl)propane-1,2,3-triol

There total 1 articles about (1R,2R)-1-(3,4-Dimethoxyphenyl)propane-1,2,3-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 18523-76-7
(E)-3',4'-dimethoxycinnamyl alcohol

: 499135-15-8
1-(3,4-dimethoxyphenyl)-1(R),2(R),3-trihydroxypentane

Guidance literature:: With methanesulfonamide; AD-mix-β; In water; tert-butyl alcohol; at 0 ℃; for 48h;
DOI:10.1021/jo020744q

Reference yield: 71.0%

: 499135-15-8
1-(3,4-dimethoxyphenyl)-1(R),2(R),3-trihydroxypentane

: 522607-76-7
(R)-(3,4-Dimethoxy-phenyl)-(R)-oxiranyl-methanol

Guidance literature:: 1-(3,4-dimethoxyphenyl)-1(R),2(R),3-trihydroxypentane; With pyridine; p-toluenesulfonyl chloride; at 0 ℃;

With potassium carbonate; In methanol; dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/jo020744q

Reference yield:

: 499135-15-8
1-(3,4-dimethoxyphenyl)-1(R),2(R),3-trihydroxypentane

: 522607-77-8
(R)-2-[(R)-(3,4-Dimethoxy-phenyl)-methoxy-methyl]-oxirane

Guidance literature:: Multi-step reaction with 2 steps

1.1: TsCl; pyridine / 0 °C

1.2: 71 percent / K₂CO₃ / methanol; CH₂Cl₂ / 1 h / 0 °C

2.1: NaH / tetrahydrofuran; dimethylsulfoxide / 0.67 h / 20 °C

2.2: 97 percent / 4 h

With pyridine; sodium hydride; p-toluenesulfonyl chloride; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/jo020744q