N-Benzoyl-alpha-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-L-phenylalanine

Base Information

Chemical Name:N-Benzoyl-alpha-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-L-phenylalanine
CAS No.:499214-14-1
Molecular Formula:C24H23NO6S
Molecular Weight:453.516
Hs Code.:
DSSTox Substance ID:DTXSID301162195
Nikkaji Number:J1.809.384G

Synonyms:DTXSID301162195;499214-14-1;N-Benzoyl-alpha-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-L-phenylalanine

Suppliers and Price of N-Benzoyl-alpha-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-L-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-Benzoyl-alpha-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-L-phenylalanine

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:453.12460863
Heavy Atom Count:32
Complexity:728

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OCC(CC2=CC=CC=C2)(C(=O)O)NC(=O)C3=CC=CC=C3
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)OC[C@](CC2=CC=CC=C2)(C(=O)O)NC(=O)C3=CC=CC=C3

Technology Process of N-Benzoyl-alpha-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-L-phenylalanine

There total 3 articles about N-Benzoyl-alpha-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-L-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2566-22-5,2901-76-0,37002-52-1
DL-N-benzoylphenylalanine

: 499214-14-1
(R)-2-benzoylamino-2-benzyl-3-tosylpropanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: Ac₂O / 1 h / 95 °C

2.1: 121 g / pyridine / H₂O / 12 h / 20 °C

3.1: aq. NaOH / dioxane / 1 h / 20 °C

3.2: cinchonidine / ethanol / 6 h

3.3: aq. HCl / 0.5 h

4.1: 90 percent / pyridine / 72 h / 5 °C

With pyridine; sodium hydroxide; acetic anhydride; In 1,4-dioxane; water;
DOI:10.1248/cpb.50.1362

Reference yield:

: 5874-61-3,21453-79-2,51127-19-6,75658-67-2
4-benzyl-2-phenyl-2-oxazolin-5-one

: 499214-14-1
(R)-2-benzoylamino-2-benzyl-3-tosylpropanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: 121 g / pyridine / H₂O / 12 h / 20 °C

2.1: aq. NaOH / dioxane / 1 h / 20 °C

2.2: cinchonidine / ethanol / 6 h

2.3: aq. HCl / 0.5 h

3.1: 90 percent / pyridine / 72 h / 5 °C

With pyridine; sodium hydroxide; In 1,4-dioxane; water;
DOI:10.1248/cpb.50.1362

Reference yield:

: 51127-28-7
(RS)-5-benzoylamino-5-benzyl-4-oxo-1,3-dioxane

: 499214-14-1
(R)-2-benzoylamino-2-benzyl-3-tosylpropanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. NaOH / dioxane / 1 h / 20 °C

1.2: cinchonidine / ethanol / 6 h

1.3: aq. HCl / 0.5 h

2.1: 90 percent / pyridine / 72 h / 5 °C

With pyridine; sodium hydroxide; In 1,4-dioxane;
DOI:10.1248/cpb.50.1362