5-Isoxazoleacetic acid

Base Information

Chemical Name:5-Isoxazoleacetic acid
CAS No.:4992-21-6
Molecular Formula:C5H5NO3
Molecular Weight:127.1
Hs Code.:
European Community (EC) Number:958-874-2

Synonyms:5-Isoxazoleacetic acid;4992-21-6;2-(1,2-oxazol-5-yl)acetic acid;MFCD19229329;5-Isoxazoleaceticacid;Isoxazol-5-yl-acetic acid;SCHEMBL1650609;XQFWVJKTSSNQMC-UHFFFAOYSA-N;AC1452;AKOS006380200;CS-12834;SY226123;EN300-106130;A914163;Z1205495543

Suppliers and Price of 5-Isoxazoleacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5-Isoxazoleacetic acid

Chemical Property:

XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:127.026943022
Heavy Atom Count:9
Complexity:115

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(ON=C1)CC(=O)O

Technology Process of 5-Isoxazoleacetic acid

There total 2 articles about 5-Isoxazoleacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4992-19-2
(3-nitro-propionyl)-malonic acid diethyl ester

: 4992-21-6
1,2-oxazol-5-ylacetic acid

Guidance literature:: Multistep reaction; (i) HBr, PBr₃, AcOH, (ii) aq. HCl;
DOI:10.1248/cpb.14.89

Reference yield:

: 4992-21-6
1,2-oxazol-5-ylacetic acid

Guidance literature:

Reference yield: 55.0%

: 1291986-72-5
methyl 3-amino-4-(1-ethyl-propylamino)-benzoate

: 4992-21-6
1,2-oxazol-5-ylacetic acid

: 1586791-52-7
4-(1-ethyl-propylamino)-3-(2-isoxazol-5-yl-acetylamino)-benzoic acid methyl ester

Guidance literature:: With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 16h;