1-piperazinecarboxylic acid, 4-[(3-hydroxyphenyl)methyl]-

Base Information

Chemical Name:1-piperazinecarboxylic acid, 4-[(3-hydroxyphenyl)methyl]-
CAS No.:500013-36-5
Molecular Formula:C16H24N2O3
Molecular Weight:292.378
Hs Code.:2933599090
Mol file:500013-36-5.mol

Synonyms:N-BOC-4-(2-ETHOXYCARBONYL-ACETYL)-PIPERIDINE;4-(2-ethoxycarbonylacetyl)piperidine-1-carboxylic acid tert-butyl ester;1-Boc-4-(2-Ethoxycarbonyl-acetyl)piperidine;N-(T-BUTOXYCARBONYL)-4-(2-ETHOXYCARBONYL-ACETYL) PIPERIDINE;4-(3-hydroxy-benzyl)-piperazine-1-carboxylic acid tert-butyl ester;

Suppliers and Price of 1-piperazinecarboxylic acid, 4-[(3-hydroxyphenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate
500mg
$ 237.00

Biosynth Carbosynth
tert-Butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate
500 mg
$ 150.00

Biosynth Carbosynth
tert-Butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate
250 mg
$ 85.00

Biosynth Carbosynth
tert-Butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate
5 g
$ 868.00

Biosynth Carbosynth
tert-Butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate
2 g
$ 434.00

Biosynth Carbosynth
tert-Butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate
1 g
$ 255.00

AK Scientific
tert-Butyl4-(3-hydroxybenzyl)piperazine-1-carboxylate
1g
$ 251.00

Total 3 raw suppliers

Chemical Property of 1-piperazinecarboxylic acid, 4-[(3-hydroxyphenyl)methyl]-

Chemical Property:

PSA：53.01000
LogP:2.32070

Purity/Quality:

98%min ^*data from raw suppliers

tert-Butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-piperazinecarboxylic acid, 4-[(3-hydroxyphenyl)methyl]-

There total 3 articles about 1-piperazinecarboxylic acid, 4-[(3-hydroxyphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 100-83-4
meta-hydroxybenzaldehyde

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 500013-36-5
tert-butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; at 20 ℃;
DOI:10.1016/j.bioorg.2021.105581

Reference yield: 84.0%

: 131362-25-9
[3-(bromomethyl)-phenoxy]dimethyl(1,1-dimethylethyl)silane

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 500013-36-5
tert-butyl 4-(3-hydroxybenzyl)piperazine-1-carboxylate

Guidance literature:: 1-t-Butoxycarbonylpiperazine; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 1h;

[3-(bromomethyl)-phenoxy]dimethyl(1,1-dimethylethyl)silane; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 24h;

With water; In DMF (N,N-dimethyl-formamide); for 0.5h;