(5R)-5-methylimidazolidine-2,4-dione

Base Information

Chemical Name:(5R)-5-methylimidazolidine-2,4-dione
CAS No.:55147-68-7
Molecular Formula:C4H6N2O2
Molecular Weight:114.1
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90364603
Nikkaji Number:J686.190C
Wikidata:Q27167056
ChEMBL ID:CHEMBL1394088
Mol file:55147-68-7.mol

Synonyms:55147-68-7;(5R)-5-methylimidazolidine-2,4-dione;Methylhydantoin-5-(D);(R)-5-METHYLHYDANTOIN;(R)-5-methylimidazolidine-2,4-dione;(R)-(+)-5-Methylhydantoin;Prestwick_214;SR-01000872638;5(R)-Methylimidazolidine-2,4-dione;5-methylhydantoin-(D);Prestwick0_000864;Prestwick1_000864;Prestwick2_000864;(5R)-5-Methylhydantoin;D-5-Methylhydantoin;SPBio_002828;SCHEMBL6100849;CHEMBL1394088;CHEBI:95229;DTXSID90364603;HMS1570N09;HMS3714N09;AKOS006272225;CCG-220864;NCGC00016847-01;NCGC00016847-02;CAS-40856-73-3;CAS-55147-68-7;(R)-5-Methylhydantoin (app 80per cent ee);SW196523-4;SR-01000872638-1;SR-01000872638-2;Q27167056

Suppliers and Price of (5R)-5-methylimidazolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R)-5-METHYLHYDANTOIN 95.00%
5MG
$ 504.53

Medical Isotopes, Inc.
(R)-5-Methylhydantoin
5 g
$ 1600.00

TRC
(R)-5-Methylhydantoin(app80%ee)
250mg
$ 130.00

Total 10 raw suppliers

Chemical Property of (5R)-5-methylimidazolidine-2,4-dione

Chemical Property:

Melting Point:175-177°C
PSA：58.20000
Density:1.216g/cm³
LogP:-0.12810
Storage Temp.:-20°C Freezer
Solubility.:Ethanol, Methanol, Water
XLogP3:-0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:114.042927438
Heavy Atom Count:8
Complexity:143

Purity/Quality:

98%Min ^*data from raw suppliers

(R)-5-METHYLHYDANTOIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(=O)NC(=O)N1
Isomeric SMILES:C[C@@H]1C(=O)NC(=O)N1
Uses A metabolite of Dihydropyrimidinase as a chiral substrate. (R)-5-Methylhydantoin (app 80% ee) is a chiral substrate of dihydropyrimidinase.

Technology Process of (5R)-5-methylimidazolidine-2,4-dione

There total 3 articles about (5R)-5-methylimidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 338-69-2,25191-17-7,18875-37-1
D-Alanine

: 55147-68-7,616-03-5
(5R)-5-methylimidazolidine-2,4-dione

Guidance literature:: D-Alanine; With potassium cyanide; In water; at 90 ℃; for 2h; Inert atmosphere;

With hydrogenchloride; In water; at 90 ℃; for 1h; Inert atmosphere;
DOI:10.1055/s-0036-1591924

Reference yield: 53.0%

: 590-28-3
potassium cyanate

: 338-69-2,25191-17-7,18875-37-1
D-Alanine

: 55147-68-7,616-03-5
(5R)-5-methylimidazolidine-2,4-dione

Guidance literature:: potassium cyanate; D-Alanine; In water; for 1h; Reflux;

With hydrogenchloride; In water; for 0.25h; Reflux;
DOI:10.1021/acs.orglett.0c00642