2-Oxazolidinone, 3-[(2S,3R,5R,6R,7R,8S,10E)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2- ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-1-oxo-10-dodecenyl]-4-(phenyl methyl)-, (4S)-

Base Information

Chemical Name:2-Oxazolidinone, 3-[(2S,3R,5R,6R,7R,8S,10E)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2- ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-1-oxo-10-dodecenyl]-4-(phenyl methyl)-, (4S)-
CAS No.:500220-39-3
Molecular Formula:C₃₃H₅₅NO₆Si
Molecular Weight:589.888
Hs Code.:

2-Oxazolidinone,
3-[(2S,3R,5R,6R,7R,8S,10E)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-
ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-1-oxo-10-dodecenyl]-4-(phenyl
methyl)-, (4S)-

Synonyms:

Suppliers and Price of 2-Oxazolidinone, 3-[(2S,3R,5R,6R,7R,8S,10E)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2- ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-1-oxo-10-dodecenyl]-4-(phenyl methyl)-, (4S)-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Oxazolidinone, 3-[(2S,3R,5R,6R,7R,8S,10E)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2- ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-1-oxo-10-dodecenyl]-4-(phenyl methyl)-, (4S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Oxazolidinone, 3-[(2S,3R,5R,6R,7R,8S,10E)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2- ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-1-oxo-10-dodecenyl]-4-(phenyl methyl)-, (4S)-

There total 14 articles about 2-Oxazolidinone, 3-[(2S,3R,5R,6R,7R,8S,10E)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2- ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-1-oxo-10-dodecenyl]-4-(phenyl methyl)-, (4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 111292-87-6,143097-11-4,112459-79-7
(S)-4-benzyl-3-butyryloxazolidin-2-one

: 182744-59-8
(E,3R,4S,5R,6S)-3-(tert-butyldimethylsilanyloxy)-5-methoxy-4,6-dimethyldec-8-enal

: 500220-39-3
(S)-4-Benzyl-3-[(E)-(2S,3R,5R,6R,7R,8S)-5-(tert-butyl-dimethyl-silanyloxy)-2-ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-dodec-10-enoyl]-oxazolidin-2-one

Guidance literature:: With di-n-butylboryl trifluoromethanesulfonate; In dichloromethane; at -78 ℃; for 6h;
DOI:10.1016/0040-4039(96)01413-X

Reference yield:

: 182744-54-3
(E)-(2S,3R,4S)-2,4-Dimethyl-oct-6-ene-1,3-diol

: 500220-39-3
(S)-4-Benzyl-3-[(E)-(2S,3R,5R,6R,7R,8S)-5-(tert-butyl-dimethyl-silanyloxy)-2-ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-dodec-10-enoyl]-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 13 steps

1: imidazole / CH₂Cl₂ / 3 h / Ambient temperature

2: KH / diethyl ether / 0.5 h / Ambient temperature

3: Bu₄NF / tetrahydrofuran / 2 h / Ambient temperature

4: o-iodoxybenzoic acid / dimethylsulfoxide / 0.5 h / Ambient temperature

5: benzene / 3 h / Ambient temperature

6: DIBAL-H / CH₂Cl₂ / 0.75 h / -20 °C

7: TBHP, TTIP, (+)DIPT / CH₂Cl₂ / 18 h / -20 °C

8: 77 percent / Red-Al / tetrahydrofuran / 4 h / 0 °C

9: pyridine / CH₂Cl₂ / 1 h / Ambient temperature

10: 2,6-lutidine / CH₂Cl₂ / 0.08 h / 0 °C

11: DIBAL-H / CH₂Cl₂ / 0.33 h / -20 °C

12: o-iodoxybenzoic acid / dimethylsulfoxide / 0.5 h / Ambient temperature

13: Bu₂BOTf / CH₂Cl₂ / 6 h / -78 °C

With pyridine; 1H-imidazole; 2,6-dimethylpyridine; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate; di-n-butylboryl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; potassium hydride; diisobutylaluminium hydride; sodium bis(2-methoxyethoxy)aluminium dihydride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; diethyl ether; dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1016/0040-4039(96)01413-X

Reference yield:

: 332842-68-9
(E)-(2R,3R,4S)-3-Methoxy-2,4-dimethyl-oct-6-enal

: 500220-39-3
(S)-4-Benzyl-3-[(E)-(2S,3R,5R,6R,7R,8S)-5-(tert-butyl-dimethyl-silanyloxy)-2-ethyl-3-hydroxy-7-methoxy-6,8-dimethyl-dodec-10-enoyl]-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 9 steps

1: benzene / 3 h / Ambient temperature

2: DIBAL-H / CH₂Cl₂ / 0.75 h / -20 °C

3: TBHP, TTIP, (+)DIPT / CH₂Cl₂ / 18 h / -20 °C

4: 77 percent / Red-Al / tetrahydrofuran / 4 h / 0 °C

5: pyridine / CH₂Cl₂ / 1 h / Ambient temperature

6: 2,6-lutidine / CH₂Cl₂ / 0.08 h / 0 °C

7: DIBAL-H / CH₂Cl₂ / 0.33 h / -20 °C

8: o-iodoxybenzoic acid / dimethylsulfoxide / 0.5 h / Ambient temperature

9: Bu₂BOTf / CH₂Cl₂ / 6 h / -78 °C

With pyridine; 2,6-dimethylpyridine; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate; di-n-butylboryl trifluoromethanesulfonate; diisobutylaluminium hydride; sodium bis(2-methoxyethoxy)aluminium dihydride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1016/0040-4039(96)01413-X