(R)-1-(2-Piperidyl)acetone hydrochloride

Base Information

Chemical Name:(R)-1-(2-Piperidyl)acetone hydrochloride
CAS No.:6152-82-5
Molecular Formula:C8H15 N O . Cl H
Molecular Weight:177.674
Hs Code.:2933399090
European Community (EC) Number:228-167-7
UNII:90YI67H3XJ
DSSTox Substance ID:DTXSID10977077
Mol file:6152-82-5.mol

Synonyms:(R)-1-(2-Piperidyl)acetone hydrochloride;6152-82-5;Pelletierine hydrochloride, (-)-;UNII-90YI67H3XJ;(-)-pelletierine hydrochloride;90YI67H3XJ;(R)-1-(2-Piperidyl)acetone HCl;EINECS 228-167-7;1-[(2R)-piperidin-2-yl]propan-2-one;hydrochloride;2-Piperidinepropionaldehyde, hydrochloride;2-Propanone, 1-(2-piperidinyl)-, hydrochloride, (R)-;DTXSID10977077;(R)-(-)-PELLETIERINE HYDROCHLORIDE;Q27271350;1-(Piperidin-2-yl)propan-2-one--hydrogen chloride (1/1);2-PROPANONE, 1-(2R)-2-PIPERIDINYL-, HYDROCHLORIDE (1:1)

Suppliers and Price of (R)-1-(2-Piperidyl)acetone hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (R)-1-(2-Piperidyl)acetone hydrochloride

Chemical Property:

Vapor Pressure:0.429mmHg at 25°C
Boiling Point:195°C at 760 mmHg
Flash Point:74.3°C
PSA：29.10000
LogP:2.23840
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:177.0920418
Heavy Atom Count:11
Complexity:122

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)CC1CCCCN1.Cl
Isomeric SMILES:CC(=O)C[C@H]1CCCCN1.Cl

Technology Process of (R)-1-(2-Piperidyl)acetone hydrochloride

There total 6 articles about (R)-1-(2-Piperidyl)acetone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1202039-12-0
(+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid tert-butylester

: 6152-82-5
(R)-(-)-pelletierine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 16h;
DOI:10.1021/jo100415x

Reference yield:

: C₈H₁₆BrNO*ClH

: 6152-82-5
(R)-(-)-pelletierine hydrochloride

Guidance literature:: C₈H₁₆BrNO*ClH; With sodium hydrogencarbonate; In dichloromethane; at 23 ℃; for 12h;

With hydrogenchloride; In diethyl ether; for 0.25h;
DOI:10.1021/acs.joc.7b01178

Reference yield:

: 182343-60-8
2-(2-propenyl)-1-piperidinecarboxylic acid tert-butyl ester

: 6152-82-5
(R)-(-)-pelletierine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: oxygen; copper diacetate; palladium dichloride / water; N,N-dimethyl-formamide / 24 h / 50 °C / 760.05 Torr

2: hydrogenchloride / 1,4-dioxane; dichloromethane / 2 h / 0 - 23 °C / Inert atmosphere

With hydrogenchloride; oxygen; copper diacetate; palladium dichloride; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; 1: Wacker oxidation;
DOI:10.1021/jo202211u