protohypericin

Base Information

• Chemical Name: protohypericin
• CAS No.: 548-03-8
• Molecular Formula: C₃₀H₁₈O₈
• Molecular Weight: 506.468
• Hs Code.: 2914400090
• Mol file: 548-03-8.mol

Synonyms:Helianthrone,1,3,4,6,8,15-hexahydroxy-10,13-dimethyl- (6CI); Protohypericin

Chemical Property of protohypericin

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 954.3°Cat760mmHg
• PKA: 5.63±0.20(Predicted)
• Flash Point: 544.7°C
• PSA: 121.38000
• Density: 1.736g/cm³
• LogP: 6.89400

Purity/Quality:

99%+, ^*data from raw suppliers

Protohypericin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of protohypericin

There total 1 articles about protohypericin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

emodinanthrone (491-60-1) + (E)-9,10-dihydro-6-(2-(4-dimethylaminophenyl)ethenyl)-1,3,8-trihydroxyanthracen-9-one (428854-18-6) → protohypericin (548-03-8,54328-08-4) + 10-[2-(4-dimethylamino-phenyl)-vinyl]-1,3,4,6,8,15-hexahydroxy-13-methyl-dibenzo[a,o]perylene-7,16-dione (428854-25-5) + 10,13-bis-[2-(4-dimethylamino-phenyl)-vinyl]-1,3,4,6,8,15-hexahydroxy-dibenzo[a,o]perylene-7,16-dione

Guidance literature:

With piperidine; pyridine N-oxide; iron(II) sulfate; In pyridine; at 100 - 110 ℃; for 1h; Title compound not separated from byproducts;

DOI:10.1007/s007060170009

upstream raw materials:

emodinanthrone

(E)-9,10-dihydro-6-(2-(4-dimethylaminophenyl)ethenyl)-1,3,8-trihydroxyanthracen-9-one

Refernces