Butanoyl chloride, 2-methyl-

Base Information

Chemical Name:Butanoyl chloride, 2-methyl-
CAS No.:57526-28-0
Deprecated CAS:5856-79-1
Molecular Formula:C₅H₉ClO
Molecular Weight:120.579
Hs Code.:29130000
European Community (EC) Number:260-787-3
DSSTox Substance ID:DTXSID70872039
Mol file:57526-28-0.mol

Synonyms:57526-28-0;2-Methylbutanoyl chloride;Butanoyl chloride, 2-methyl-;dl-2-Methylbutyryl chloride;2-Methylbutyryl chloride;Ethylmethylacetylchloride;DL-2-Methylbutyrylchloride;Dl-2-Methyl-Butyryl Chloride;5856-79-1;(RS)-2-Methylbutyryl chloride;(R)-2-MethylbutyricAcidChloride-d3;EINECS 260-787-3;MFCD00041726;2-methyl-butyryl chloride;2-Methylbutanoyl chloride #;SCHEMBL505184;2-Methylbutyryl chloride, 97%;DL-2-Methyl-N-butyryl chloride;(+)-2-methyl butanoyl chloride;XRPVXVRWIDOORM-UHFFFAOYSA-;DTXSID70872039;(+/-)-2-Methylbutyryl chloride;2-METHYLBUTYRYL-D9 CHLORIDE;(+)-2-methylbutanoic acid chloride;AKOS009158813;Butanoyl chloride, 2-methyl-, (.+.)-;Butanoyl chloride, 2-methyl-, (.+/-.)-;FT-0613031;FT-0624374;FT-0671576

Suppliers and Price of Butanoyl chloride, 2-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methylbutyryl chloride
5 g
$ 70.00

Sigma-Aldrich
2-Methylbutyryl chloride 97%
5g
$ 73.70

Medical Isotopes, Inc.
2-Methylbutyryl chloride
2.5 g
$ 675.00

American Custom Chemicals Corporation
2-METHYLBUTYRYL CHLORIDE 95.00%
1G
$ 1030.84

Alfa Aesar
2-Methylbutyryl chloride, 99%
100g
$ 256.00

Alfa Aesar
2-Methylbutyryl chloride, 99%
25g
$ 118.00

Alfa Aesar
2-Methylbutyryl chloride, 99%
5g
$ 49.00

AHH
DL-2-Methylbutyrylchloride 98%
500g
$ 668.00

Total 27 raw suppliers

Chemical Property of Butanoyl chloride, 2-methyl-

Chemical Property:

Appearance/Colour:clear colorless to light yellow liquid
Vapor Pressure:18.2mmHg at 25°C
Refractive Index:n20/D 1.418(lit.)
Boiling Point:116.4 °C at 760 mmHg
Flash Point:25.5 °C
PSA：17.07000
Density:1.005 g/cm³
LogP:1.79790
Storage Temp.:Refrigerator (+4°C) + Flammables area
Water Solubility.:Reacts with water.
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:120.0341926
Heavy Atom Count:7
Complexity:70.5

Purity/Quality:

99% ^*data from raw suppliers

2-Methylbutyryl chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,C
Hazard Codes:F,C
Statements: 11-34
Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCC(C)C(=O)Cl
Uses 2-Methylbutyryl chloride was used in the synthesis of 2-methylbutyramide, N-((R,S)-2-methylbutanoyl)salicylhydrazide, 2-methyl-1-phenyl-1-butanone, 1,1?-(1,3,7,9-tetrahydroxydibenzofuran-2,6-diyl)bis(2-methylbutan-1-one).

Technology Process of Butanoyl chloride, 2-methyl-

There total 10 articles about Butanoyl chloride, 2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 116-53-0,600-07-7
2-Methylbutanoic acid

: 5856-79-1,57526-28-0
iso-butyl chloroformate

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide; at 40 ℃; for 2h;
DOI:10.1002/ejoc.200700015

Reference yield:

: 116-53-0,600-07-7
2-Methylbutanoic acid

: 7719-09-7
thionyl chloride

: 5856-79-1,57526-28-0
iso-butyl chloroformate

Guidance literature:: In dichloromethane; at 25 ℃; for 12h;
DOI:10.1021/jm901229s

Reference yield:

: 119520-53-5
2-Methyl-N-pyridin-3-yl-butyramide

: 5856-79-1,57526-28-0
iso-butyl chloroformate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) hexamethyldisilazane, 1.6 M n-BuLi, 2.) CS₂, 3.) PhSeO₂H / 1.) THF, hexane, -20 deg C, 30 min, 2.) THF, rt, 3.) THF, rt, 5 h

2: oxalyl chloride, DMF / benzene / Ambient temperature

With carbon disulfide; n-butyllithium; oxalyl dichloride; benzeneseleninic acid; N,N-dimethyl-formamide; 1,1,1,3,3,3-hexamethyl-disilazane; In benzene;
DOI:10.1016/S0040-4020(01)85980-9