11-Oxa-2,6,9-triazatridecanoic acid, 2-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-4-hydroxy-12,12-dimethyl-8-(1 -methylethyl)-7,10-dioxo-5-(phenylmethyl)-, phenylmethyl ester, (4S,5S,8S)-

Base Information

Chemical Name:11-Oxa-2,6,9-triazatridecanoic acid, 2-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-4-hydroxy-12,12-dimethyl-8-(1 -methylethyl)-7,10-dioxo-5-(phenylmethyl)-, phenylmethyl ester, (4S,5S,8S)-
CAS No.:500767-27-1
Molecular Formula:C34H50N4O7
Molecular Weight:626.794
Hs Code.:

11-Oxa-2,6,9-triazatridecanoic acid,
2-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-4-hydroxy-12,12-dimethyl-8-(1
-methylethyl)-7,10-dioxo-5-(phenylmethyl)-, phenylmethyl ester,
(4S,5S,8S)-

Synonyms:

Suppliers and Price of 11-Oxa-2,6,9-triazatridecanoic acid, 2-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-4-hydroxy-12,12-dimethyl-8-(1 -methylethyl)-7,10-dioxo-5-(phenylmethyl)-, phenylmethyl ester, (4S,5S,8S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 11-Oxa-2,6,9-triazatridecanoic acid, 2-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-4-hydroxy-12,12-dimethyl-8-(1 -methylethyl)-7,10-dioxo-5-(phenylmethyl)-, phenylmethyl ester, (4S,5S,8S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 11-Oxa-2,6,9-triazatridecanoic acid, 2-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-4-hydroxy-12,12-dimethyl-8-(1 -methylethyl)-7,10-dioxo-5-(phenylmethyl)-, phenylmethyl ester, (4S,5S,8S)-

There total 5 articles about 11-Oxa-2,6,9-triazatridecanoic acid, 2-[(1S)-1-(aminocarbonyl)-3-methylbutyl]-4-hydroxy-12,12-dimethyl-8-(1 -methylethyl)-7,10-dioxo-5-(phenylmethyl)-, phenylmethyl ester, (4S,5S,8S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13734-41-3
t-Boc-L-valine

: ((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-((S)-1-carbamoyl-3-methyl-butyl)-carbamic acid benzyl ester

: 500767-27-1
(2S,5S,6S)-3-aza-3-(benzyloxycarbonyl)-6-[[(tert-butyloxycarbonyl)-L-valinyl]amino]-2-isobutyl-5-hydroxy-7-phenylheptanoyl amide

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/jm020951i

Reference yield:

: 687-51-4,13079-20-4,13366-40-0,15893-47-7
H-L-Leu-NH₂

: 500767-27-1
(2S,5S,6S)-3-aza-3-(benzyloxycarbonyl)-6-[[(tert-butyloxycarbonyl)-L-valinyl]amino]-2-isobutyl-5-hydroxy-7-phenylheptanoyl amide

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / propan-2-ol / Heating

2: 100 percent / aq. K₂CO₃ / tetrahydrofuran / 20 °C

3: HCl / ethyl acetate / 20 °C

4: 87 mg / TBTU; DIEA / dimethylformamide / 20 °C

With hydrogenchloride; potassium carbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm020951i

Reference yield:

: 98760-08-8
(2R,3S)-3-[N-(tert-butyloxycarbonyl)amino]-1,2-epoxy-4-phenylbutane

: 500767-27-1
(2S,5S,6S)-3-aza-3-(benzyloxycarbonyl)-6-[[(tert-butyloxycarbonyl)-L-valinyl]amino]-2-isobutyl-5-hydroxy-7-phenylheptanoyl amide

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / propan-2-ol / Heating

2: 100 percent / aq. K₂CO₃ / tetrahydrofuran / 20 °C

3: HCl / ethyl acetate / 20 °C

4: 87 mg / TBTU; DIEA / dimethylformamide / 20 °C

With hydrogenchloride; potassium carbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm020951i