1(2H)-Pyrazinecarboxylic acid, 3,4-dihydro-4-[[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]-2-( 1-naphthalenylmethyl)-3-oxo-, phenylmethyl ester, (2S)-

Base Information

• Chemical Name: 1(2H)-Pyrazinecarboxylic acid, 3,4-dihydro-4-[[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]-2-( 1-naphthalenylmethyl)-3-oxo-, phenylmethyl ester, (2S)-
• CAS No.: 500782-97-8
• Molecular Formula: C₄₇H₄₀N₄O₃
• Molecular Weight: 708.86
• Mol file: 500782-97-8.mol

Synonyms:

Chemical Property of 1(2H)-Pyrazinecarboxylic acid, 3,4-dihydro-4-[[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]-2-( 1-naphthalenylmethyl)-3-oxo-, phenylmethyl ester, (2S)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1(2H)-Pyrazinecarboxylic acid, 3,4-dihydro-4-[[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]-2-( 1-naphthalenylmethyl)-3-oxo-, phenylmethyl ester, (2S)-

There total 6 articles about 1(2H)-Pyrazinecarboxylic acid, 3,4-dihydro-4-[[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]-2-( 1-naphthalenylmethyl)-3-oxo-, phenylmethyl ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C25H28N2O5 (500782-92-3) → C47H40N4O3 (500782-97-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 25 percent / TFA / H₂O / 20 °C

2: NaH / tetrahydrofuran

With sodium hydride; trifluoroacetic acid; In tetrahydrofuran; water;

DOI:10.1039/b517572k

Reference yield:

trityl chloride (76-83-5) → C47H40N4O3 (500782-97-8)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / dimethylformamide

2: 80 percent / SOCl₂ / dimethylformamide; CH₂Cl₂ / 0.25 h / 0 °C

3: NaH / tetrahydrofuran

With thionyl chloride; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/b517572k

Reference yield:

4-Hydroxymethyl-5-methyl-1-(triphenylmethyl)imidazole (106147-84-6) → C47H40N4O3 (500782-97-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / SOCl₂ / dimethylformamide; CH₂Cl₂ / 0.25 h / 0 °C

2: NaH / tetrahydrofuran

With thionyl chloride; sodium hydride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/b517572k

upstream raw materials:

C₂₃H₂₀N₂O₃

4-chloromethyl-5-methyl-1-tritylimidazole

C₂₅H₂₈N₂O₅

trityl chloride

Downstream raw materials:

C₃₉H₃₆N₄O

C₄₇H₄₉N₅O₄