1,2,3-Oxadiazolium,3,3'-(1,4-phenylene)bis[5-hydroxy-, bis(inner salt)

Base Information

• Chemical Name: 1,2,3-Oxadiazolium,3,3'-(1,4-phenylene)bis[5-hydroxy-, bis(inner salt)
• CAS No.: 10301-11-8
• Molecular Formula: C10H6 N4 O4
• Molecular Weight: 246.182
• Mol file: 10301-11-8.mol

Synonyms:Sydnone,3,3'-(1,4-phenylene)bis-; Sydnone, 3,3'-p-phenylenedi- (7CI,8CI);3,3'-(p-Phenylene)bis(sydnone); 3,3'-p-Phenylenedi(sydnone); NSC 97854;p-Phenylenebis(3-sydnone)

Chemical Property of 1,2,3-Oxadiazolium,3,3'-(1,4-phenylene)bis[5-hydroxy-, bis(inner salt)

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,3-Oxadiazolium,3,3'-(1,4-phenylene)bis[5-hydroxy-, bis(inner salt)

There total 5 articles about 1,2,3-Oxadiazolium,3,3'-(1,4-phenylene)bis[5-hydroxy-, bis(inner salt) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N,N’-dinitroso-p-phenylenediamine-N,N’-diacetic acid (6645-64-3) → 3-4-(5-oxido-1,2,3)4-oxadiazol-3-yl-phenyl-1,2,3-oxadiazol-3-ium-5-olate (10301-11-8)

Guidance literature:

With trifluoroacetic anhydride; In dichloromethane; at 0 - 45 ℃; Inert atmosphere;

DOI:10.1021/jacs.6b03381

Reference yield:

N,N'-(1,4-phenylene)bis(glycine) (10097-07-1) → 3-4-(5-oxido-1,2,3)4-oxadiazol-3-yl-phenyl-1,2,3-oxadiazol-3-ium-5-olate (10301-11-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite; acetic acid / water / 0 - 5 °C

2: trifluoroacetic anhydride / dichloromethane / 0 - 45 °C / Inert atmosphere

With acetic acid; trifluoroacetic anhydride; sodium nitrite; In dichloromethane; water;

DOI:10.1021/jacs.6b03381

Reference yield:

1,4-phenylenediamine (106-50-3) → 3-4-(5-oxido-1,2,3)4-oxadiazol-3-yl-phenyl-1,2,3-oxadiazol-3-ium-5-olate (10301-11-8)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium acetate / ethanol / 80 °C / Inert atmosphere

2: sodium hydroxide / ethanol; water / 0.5 h / 100 °C

3: sodium nitrite; acetic acid / water / 0 - 5 °C

4: trifluoroacetic anhydride / dichloromethane / 0 - 45 °C / Inert atmosphere

With sodium acetate; acetic acid; trifluoroacetic anhydride; sodium hydroxide; sodium nitrite; In ethanol; dichloromethane; water;

DOI:10.1021/jacs.6b03381

upstream raw materials:

N,N’-dinitroso-p-phenylenediamine-N,N’-diacetic acid

1,4-phenylenediamine

N,N'-(1,4-phenylene)bis(glycine)

Downstream raw materials:

3,5,9,11-tetraoxo-4,10-diphenyl-(1,4-bis(1,4,10,13-tetrazatetracyclo<5.5.1.0.^2,60^8,12>-13-tridecyl)benzene)