Technology Process of Methyl(2,4,6-trimethylphenyl)phosphane
There total 1 articles about Methyl(2,4,6-trimethylphenyl)phosphane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,4,6-trimethylphenyl bromide;
With
magnesium;
In
tetrahydrofuran;
at 20 ℃;
methyldichlorophosphane;
In
tetrahydrofuran; diethyl ether;
Heating;
With
lithium aluminium tetrahydride;
at 20 ℃;
for 2.5h;
Further stages.;
DOI:10.1021/ja070225a
- Guidance literature:
-
With
sodium trimethylsilanolate;
dichlorobis(tri-O-tolylphosphine)palladium;
In
tetrahydrofuran; benzene;
for 20h;
Heating;
DOI:10.1021/ja070225a
- Guidance literature:
-
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
dichloromethane;
byproducts: (DBUH)(BPh4); (N2); using Schlenk techniques; suspending of CpMn(CO)2(CPh)BPh4 in CH2Cl2 at -50°C, addn. of HP(Me)Mes via syringe under stirring, monitoring by IR for 0.5 h, cooling to -80°C, treatment with DBU (1 equiv.), warming to room temp.; removal of solvent under vac., extn. with ether, filtration, evapn. of combined extracts under vac., recrystn. from ether-hexane; elem. anal.;
DOI:10.1021/om2000772
