Benzoic acid, 2-[[(2E)-2-(1-acetyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-(4-methoxy phenyl)-1,4-dioxobutyl]amino]-

Base Information

• Chemical Name: Benzoic acid, 2-[[(2E)-2-(1-acetyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-(4-methoxy phenyl)-1,4-dioxobutyl]amino]-
• CAS No.: 503309-35-1
• Molecular Formula: C₂₈H₂₂N₂O₇
• Molecular Weight: 498.492
• Mol file: 503309-35-1.mol

Synonyms:

Chemical Property of Benzoic acid, 2-[[(2E)-2-(1-acetyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-(4-methoxy phenyl)-1,4-dioxobutyl]amino]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 2-[[(2E)-2-(1-acetyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-(4-methoxy phenyl)-1,4-dioxobutyl]amino]-

There total 3 articles about Benzoic acid, 2-[[(2E)-2-(1-acetyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-(4-methoxy phenyl)-1,4-dioxobutyl]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) + (3E)-1-acetyl-3-[5-(4-methoxyphenyl)-2-oxofuran-3(2H)-ylidene]-1,3-dihydro-2H-indol-2-one (503309-31-7) → 2-{[(2E)-2-(1-acetyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-(4-methoxyphenyl)-4-oxobutanoyl]amino}benzoic acid (503309-35-1)

Guidance literature:

In acetic acid; for 48h; Heating;

DOI:10.1002/hc.10175

Reference yield:

indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) → 2-{[(2E)-2-(1-acetyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-(4-methoxyphenyl)-4-oxobutanoyl]amino}benzoic acid (503309-35-1)

Guidance literature:

Multi-step reaction with 2 steps

1.2: 75 percent / sodium acetate

2.1: 59 percent / acetic acid / 48 h / Heating

In acetic acid;

DOI:10.1002/hc.10175

Reference yield:

4-(4-methoxy-phenyl)-4-oxo-butyric acid (3153-44-4) → 2-{[(2E)-2-(1-acetyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-(4-methoxyphenyl)-4-oxobutanoyl]amino}benzoic acid (503309-35-1)

Guidance literature:

Multi-step reaction with 2 steps

1.2: 75 percent / sodium acetate

2.1: 59 percent / acetic acid / 48 h / Heating

In acetic acid;

DOI:10.1002/hc.10175

upstream raw materials:

anthranilic acid

(3E)-1-acetyl-3-[5-(4-methoxyphenyl)-2-oxofuran-3(2H)-ylidene]-1,3-dihydro-2H-indol-2-one

indole-2,3-dione

4-(4-methoxy-phenyl)-4-oxo-butyric acid