2,6-Diisopropylaniline hydrochloride

Base Information

• Chemical Name: 2,6-Diisopropylaniline hydrochloride
• CAS No.: 50522-40-2
• Molecular Formula: C12H19N.ClH
• Molecular Weight: 213.75
• DSSTox Substance ID: DTXSID70457961
• Mol file: 50522-40-2.mol

Synonyms:2,6-diisopropylaniline hydrochloride;50522-40-2;Benzenamine, 2,6-bis(1-methylethyl)-, hydrochloride;SCHEMBL8615487;DTXSID70457961;BGLSLIDLBHRORL-UHFFFAOYSA-N;AKOS026674366;2,6-di(propan-2-yl)aniline;hydrochloride;2,6-Di(propan-2-yl)aniline--hydrogen chloride (1/1)

Chemical Property of 2,6-Diisopropylaniline hydrochloride

Chemical Property:

• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 213.1284273
• Heavy Atom Count: 14
• Complexity: 135

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)C1=C(C(=CC=C1)C(C)C)N.Cl

Technology Process of 2,6-Diisopropylaniline hydrochloride

There total 2 articles about 2,6-Diisopropylaniline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + lithium (2,6-diisopropylphenyl)amide → BClN(C6H3(CH(CH3)2)2)CH2CH2CH2CH2O (1072955-34-0) + 2,6-diisopropylaniline hydrochloric acid salt (50522-40-2)

Guidance literature:

With boron trichloride; In hexane; at 20 ℃; for 18h;

DOI:10.1039/b810319d

Reference yield:

2,6-diisopropylbenzenamine (24544-04-5) → 2,6-diisopropylaniline hydrochloric acid salt (50522-40-2)

Guidance literature:

With hydrogenchloride; In diethyl ether; Inert atmosphere;

DOI:10.1002/poc.2978

Reference yield: 99.9%

2,6-diisopropylaniline hydrochloric acid salt (50522-40-2) → 2,6-diisopropyl-4-bromoaniline hydrobromide

Guidance literature:

With bromine; In cyclohexane;

upstream raw materials:

tetrahydrofuran

2,6-diisopropylbenzenamine

Downstream raw materials:

2,6-diisopropylphenyl isocyanate

4-bromo-2,6-diisopropylaniline

2,6-diisopropyl-4-tert-butyldiphenylsilyl-aniline

4-amino-3,5-bis(propan-2-yl)benzonitrile