N-(2-phenylethyl)-1-benzofuran-2-carboxamide

Base Information

Chemical Name:N-(2-phenylethyl)-1-benzofuran-2-carboxamide
CAS No.:50635-14-8
Molecular Formula:C17H15NO2
Molecular Weight:265.30700
Hs Code.:
DSSTox Substance ID:DTXSID40352398
Wikidata:Q82129524
Mol file:50635-14-8.mol

Synonyms:N-(2-phenylethyl)-1-benzofuran-2-carboxamide;50635-14-8;2-Benzofurancarboxamide, N-(2-phenylethyl)-;Oprea1_502266;Oprea1_759775;SCHEMBL2242298;DTXSID40352398;HMS1609K09;STK701354;AKOS000505126;AG-205/10368004;SR-01000410604;SR-01000410604-1;Z27761529

Suppliers and Price of N-(2-phenylethyl)-1-benzofuran-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(2-phenylethyl)-1-benzofuran-2-carboxamide

Chemical Property:

Boiling Point:493.9±28.0 °C(Predicted)
PKA:13.89±0.46(Predicted)
PSA：45.73000
Density:1.184±0.06 g/cm3(Predicted)
LogP:3.98010
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:265.110278721
Heavy Atom Count:20
Complexity:325

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCNC(=O)C2=CC3=CC=CC=C3O2

Technology Process of N-(2-phenylethyl)-1-benzofuran-2-carboxamide

There total 1 articles about N-(2-phenylethyl)-1-benzofuran-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.7%

: 41717-28-6
2-benzofuroyl chloride

: 64-04-0
phenethylamine

: 50635-14-8
N-phenethylbenzofuran-2-carboxamide

Guidance literature:: In benzene; for 5h;
DOI:10.1007/BF00765082

Reference yield: 90.1%

: 50635-14-8
N-phenethylbenzofuran-2-carboxamide

: 90141-24-5
4-{2-[(Benzofuran-2-carbonyl)-amino]-ethyl}-benzenesulfonyl chloride

Guidance literature:: With chlorosulphuric acid; at -5 - -1 ℃; for 2h;
DOI:10.1007/BF00765082

Reference yield:

: 50635-14-8
N-phenethylbenzofuran-2-carboxamide

: 33289-02-0
Benzofuran-2-carboxylic acid [2-(4-sulfamoyl-phenyl)-ethyl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 90.1 percent / chlorosulfuric acid / 2 h / -5 - -1 °C

2: 60 percent / aq. NH₃ / 2 h

With ammonium hydroxide; chlorosulphuric acid;
DOI:10.1007/BF00765082