Cyclopentanecarbonitrile, 1-(2-methylphenyl)-

Base Information

• Chemical Name: Cyclopentanecarbonitrile, 1-(2-methylphenyl)-
• CAS No.: 515814-32-1
• Molecular Formula: C13H15N
• Molecular Weight: 185.26500
• Mol file: 515814-32-1.mol

Synonyms:1-(o-tolyl)cyclopentane-1-carbonitrile;1-o-Tolyl-cyclopentanecarbonitrile;

Chemical Property of Cyclopentanecarbonitrile, 1-(2-methylphenyl)-

Chemical Property:

• PSA: 23.79000
• LogP: 3.33038

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Methylphenyl)cyclopentanecarbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopentanecarbonitrile, 1-(2-methylphenyl)-

There total 1 articles about Cyclopentanecarbonitrile, 1-(2-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

1,4-dibromo-butane (110-52-1) + 2-tolylmethylnitrile (22364-68-7) → 1-(2-methylphenyl)-1-cyclopentanecarbonitrile (515814-32-1)

Guidance literature:

With sodium hydride; In toluene; for 5h;

DOI:10.1023/A:1020969413371

Reference yield: 70.0%

1-(2-methylphenyl)-1-cyclopentanecarbonitrile (515814-32-1) → 1-(2-bromomethylphenyl)-1-cyclopentanecarbonitrile (515814-33-2)

Guidance literature:

With N-Bromosuccinimide; azo-bis-isobutyric acid dinitrile; In tetrachloromethane; for 14h; Heating;

DOI:10.1023/A:1020969413371

Reference yield:

1-(2-methylphenyl)-1-cyclopentanecarbonitrile (515814-32-1) → C19H19ClN2*BrH

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / N-bromosuccinimide; azodiisobutyric acid dinitrile / CCl₄ / 14 h / Heating

2: 59 percent / dioxane / 8 h / Heating

With N-Bromosuccinimide; azo-bis-isobutyric acid dinitrile; In 1,4-dioxane; tetrachloromethane;

DOI:10.1023/A:1020969413371

upstream raw materials:

1,4-dibromo-butane

2-tolylmethylnitrile

Downstream raw materials:

1-(2-bromomethylphenyl)-1-cyclopentanecarbonitrile

2-[2-(1-cyanocyclopentyl)benzylamino]benzonitrile