Ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-thiazolyl)-

Base Information

Chemical Name:Ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-thiazolyl)-
CAS No.:51625-76-4
Molecular Formula:C₁₁H₉NO₃S
Molecular Weight:235.263
Hs Code.:
DSSTox Substance ID:DTXSID70349711
Wikidata:Q82125124
ChEMBL ID:CHEMBL1469770
Mol file:51625-76-4.mol

Synonyms:51625-76-4;Ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-thiazolyl)-;1-(2,4-dihydroxyphenyl)-2-(1,3-thiazol-4-yl)ethanone;MLS000038401;Oprea1_288456;Oprea1_847826;IFLab1_000420;IFLab2_000187;CHEMBL1469770;DTXSID70349711;HMS1413D02;HMS2288N22;STL324238;AKOS002347064;IDI1_008639;IDI1_019213;NCGC00021001-01;NCGC00021001-02;SMR000038991;SR-01000002852;SR-01000002852-2

Suppliers and Price of Ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-thiazolyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-thiazolyl)-

Chemical Property:

PSA：98.66000
LogP:1.97970
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:235.03031432
Heavy Atom Count:16
Complexity:262

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1O)O)C(=O)CC2=CSC=N2

Technology Process of Ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-thiazolyl)-

There total 1 articles about Ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-thiazolyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7709-59-3
2-(thiazol-4-yl)acetonitrile

: 108-46-3
recorcinol

: 51625-76-4
2,4-dihydroxy-α-(thiazol-4-yl)acetophenone

Guidance literature:: With hydrogenchloride; boron trifluoride diethyl etherate;

Reference yield: 57.0%

: 51625-76-4
2,4-dihydroxy-α-(thiazol-4-yl)acetophenone

: 572-09-8
2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide

: 106527-55-3
Acetic acid (2R,3R,4S,5R,6S)-3,5-diacetoxy-2-acetoxymethyl-6-[3-hydroxy-4-(2-thiazol-4-yl-acetyl)-phenoxy]-tetrahydro-pyran-4-yl ester

Guidance literature:: With sodium isopropylate; In acetone; for 10h;
DOI:10.1007/BF00598526

Reference yield:

: 51625-76-4
2,4-dihydroxy-α-(thiazol-4-yl)acetophenone

: 106508-35-4
1-[2-Hydroxy-4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-2-thiazol-4-yl-ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / sodium isopropanolate / acetone / 10 h

2: 75 percent / 2N NaOH / H₂O; methanol / 0.17 h / Heating

With sodium hydroxide; sodium isopropylate; In methanol; water; acetone;
DOI:10.1007/BF00598526