5-Chloro-3-(4-chlorophenyl)isoxazole

Base Information

• Chemical Name: 5-Chloro-3-(4-chlorophenyl)isoxazole
• CAS No.: 51726-07-9
• Molecular Formula: C9H5Cl2NO
• Molecular Weight: 214.051
• DSSTox Substance ID: DTXSID80443411
• Nikkaji Number: J880.770A
• Wikidata: Q82261206
• Mol file: 51726-07-9.mol

Synonyms:5-Chloro-3-(4-chlorophenyl)isoxazole;51726-07-9;Isoxazole, 5-chloro-3-(4-chlorophenyl)-;3-(4-Chlorophenyl)-5-chloroisoxazole;SCHEMBL9213944;DTXSID80443411;HMDNAOBMBZXCSM-UHFFFAOYSA-N;AKOS017553569

Chemical Property of 5-Chloro-3-(4-chlorophenyl)isoxazole

Chemical Property:

• PSA: 26.03000
• LogP: 3.64840
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 212.9748192
• Heavy Atom Count: 13
• Complexity: 171

Purity/Quality:

99% ^*data from raw suppliers

5-CHLORO-3-(4-CHLOROPHENYL)ISOXAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C2=NOC(=C2)Cl)Cl

Technology Process of 5-Chloro-3-(4-chlorophenyl)isoxazole

There total 6 articles about 5-Chloro-3-(4-chlorophenyl)isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-(4-chlorophenyl)-1,1-dichlorocyclopropane (33489-96-2) → 3-(4-chlorophenyl)-5-chloroisoxazole (51726-07-9)

Guidance literature:

With nitrosonium tetrafluoroborate; In acetonitrile; for 1.5h; Ambient temperature;

DOI:10.1021/jo962297i

Reference yield: 73.0%

(1E)-3,3-dichloro-N-hydroxy-1-(4-chlorophenyl)prop-2-en-1-imine → 3-(4-chlorophenyl)-5-chloroisoxazole (51726-07-9)

Guidance literature:

With potassium tert-butylate; In tert-butyl alcohol; at 20 ℃; for 4h;

DOI:10.1134/S107042802011010X

Reference yield: 55.0%

2-(4-chlorophenyl)-1,1-dichlorocyclopropane (33489-96-2) → p-chlorocinnamic acid (1615-02-7,940-62-5) + 1-(4-chlorophenyl)-3,3-dichloroprop-2-en-1-one oxime (1427282-25-4) + 1,1,5,5-tetrachloro-3-(4-chlorophenyl)penta-1,4-diene (1427282-26-5) + 3-(4-chlorophenyl)-5-chloroisoxazole (51726-07-9)

Guidance literature:

With nitrosyl chloride sulfur trioxide; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1134/S1070428013020024

upstream raw materials:

2-(4-chlorophenyl)-1,1-dichlorocyclopropane

3-(4-chlorophenyl)isoxazol-5-(4H)-one

ethyl (4-chlorobenzoyl)acetate

Downstream raw materials:

3-(4-Chlorphenyl)-5-(2-morpholinoethylanilino)isoxazol

3-(4-Chlorphenyl)-5-(2-pyrrolidinoethylanilino)isoxazol

3-(4-Chlorphenyl)-5-(2-piperidinoethylanilino)isoxazol

3-(4-Chloro-phenyl)-5-oxiranylmethoxy-isoxazole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 51726-07-9 5-CHLORO-3-(4-CHLOROPHENYL)ISOXAZOLE

Send

Send

Metric Ton KG G Pound L ML

Send

Send