Oxyma

Base Information

Chemical Name:Oxyma
CAS No.:57361-81-6
Molecular Formula:C25H34 O5
Molecular Weight:414.542
Hs Code.:
European Community (EC) Number:611-512-4
DSSTox Substance ID:DTXSID60972870
Nikkaji Number:J1.945.413D
Wikidata:Q82956703
Mol file:57361-81-6.mol

Synonyms:3-methoxy-6-formyl-3,5-pregnadien-17-acetate-20-one-oxyma;oxyma

Suppliers and Price of Oxyma

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Oxyma

Chemical Property:

Vapor Pressure:5.14E-12mmHg at 25°C
Melting Point:205-208 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling Point:546.9°Cat760mmHg
Flash Point:234.7°C
PSA：69.67000
Density:1.16g/cm³
LogP:4.54940
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:414.24062418
Heavy Atom Count:30
Complexity:854

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1(CCC2C1(CCC3C2CC(=C4C3(CCC(=C4)OC)C)C=O)C)OC(=O)C
Isomeric SMILES:CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=C4[C@@]3(CCC(=C4)OC)C)C=O)C)OC(=O)C

Technology Process of Oxyma

There total 3 articles about Oxyma which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1054-64-4
17α-acetoxy-3-methoxypregna-3,5-dien-20-one

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 57361-81-6
17α-acetoxy-6-formyl-3-methoxypregna-3,5-dien-20-one

Guidance literature:: With pyridine; trichlorophosphate; In dichloromethane; at 0 - 20 ℃; for 3h;
DOI:10.1248/cpb.51.1132

Reference yield:

: 4134-58-1,17308-02-0,41460-93-9,41460-97-3,630-56-8,302-23-8
hydroxyprogesterone acetate

: 57361-81-6
17α-acetoxy-6-formyl-3-methoxypregna-3,5-dien-20-one

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / PTSA / dioxane / 1 h / 20 °C

2: 60 percent / POCl₃; pyridine / CH₂Cl₂ / 3 h / 0 - 20 °C

With pyridine; toluene-4-sulfonic acid; trichlorophosphate; In 1,4-dioxane; dichloromethane;
DOI:10.1248/cpb.52.535