1-(Difluoromethoxy)-4-ethynylbenzene

Base Information

Chemical Name:1-(Difluoromethoxy)-4-ethynylbenzene
CAS No.:519059-04-2
Molecular Formula:C9H6F2O
Molecular Weight:168.143
Hs Code.:2909309090
DSSTox Substance ID:DTXSID80380978
Wikidata:Q82171506
Mol file:519059-04-2.mol

Synonyms:1-(difluoromethoxy)-4-ethynylbenzene;519059-04-2;4-(Difluoromethoxy)phenylacetylene;SCHEMBL2794280;DTXSID80380978;1-difluoromethoxy-4-ethynylbenzene;1-difluoromethoxy-4-ethynyl-benzene;MFCD03094335;AKOS009158242;CS-0107245;D76714;EN300-1254873;A1-06889;F8883-2301

Suppliers and Price of 1-(Difluoromethoxy)-4-ethynylbenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-(Difluoromethoxy)phenylacetylene
1 g
$ 704.00

SynQuest Laboratories
4-(Difluoromethoxy)phenylacetylene
250 mg
$ 200.00

Matrix Scientific
1-(Difluoromethoxy)-4-ethynylbenzene 95%
5g
$ 1980.00

Matrix Scientific
1-(Difluoromethoxy)-4-ethynylbenzene 95%
1g
$ 990.00

Apolloscientific
4-(Difluoromethoxy)phenylacetylene 95%
250mg
$ 125.00

Apolloscientific
4-(Difluoromethoxy)phenylacetylene 95%
1g
$ 440.00

American Custom Chemicals Corporation
4-(DIFLUOROMETHOXY)PHENYLACETYLENE 95.00%
1G
$ 1495.21

A1 Biochem Labs
1-(Difluoromethoxy)-4-ethynylbenzene 95%
1 g
$ 600.00

Total 2 raw suppliers

Chemical Property of 1-(Difluoromethoxy)-4-ethynylbenzene

Chemical Property:

PSA：9.23000
LogP:2.26930
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:168.03867113
Heavy Atom Count:12
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

4-(Difluoromethoxy)phenylacetylene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C#CC1=CC=C(C=C1)OC(F)F

Technology Process of 1-(Difluoromethoxy)-4-ethynylbenzene

There total 1 articles about 1-(Difluoromethoxy)-4-ethynylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 918487-36-2
{[4-(difluoromethoxy)-phenyl]ethynyl}(trimethyl)silane

: 519059-04-2
1-(difluoromethoxy)-4-ethynylbenzene

Guidance literature:: With methanol; caesium carbonate; In dichloromethane; at 20 ℃; for 1.5h;

Reference yield: 82.0%

: 519059-04-2
1-(difluoromethoxy)-4-ethynylbenzene

: 1057324-11-4
1-bromo-3-(1,4-difluoro-butyl)benzene

: 931430-14-7
1-(3-{[4-(difluoromethoxy)phenyl]ethynyl}phenyl)-1,4-difluorobutane

Guidance literature:: With tri-tert-butyl phosphine; bis(benzonitrile)palladium(II) dichloride; In 1,4-dioxane; hexanes; at 20 ℃; for 0.25h;

With diisopropylamine; copper(l) iodide; In 1,4-dioxane; hexanes; for 0.166667h;

1-(difluoromethoxy)-4-ethynylbenzene; 1-bromo-3-(1,4-difluoro-butyl)benzene; In 1,4-dioxane; hexanes; at 20 - 35 ℃; for 3.5h;

Reference yield: 72.0%

: 519059-04-2
1-(difluoromethoxy)-4-ethynylbenzene

: 1065168-46-8
[3-(3-Bromo-phenyl)-cyclobutylidene]-acetic acid methyl ester

: 1065168-49-1
C₂₂H₁₈F₂O₃

Guidance literature:: With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 80 ℃; for 0.5h; Microwave irradiation;