1-(4-Methylphenyl)-1H-imidazole-4-carbaldehyde

Base Information

Chemical Name:1-(4-Methylphenyl)-1H-imidazole-4-carbaldehyde
CAS No.:52046-22-7
Molecular Formula:C₁₁H₁₀N₂O
Molecular Weight:186.213
Hs Code.:
DSSTox Substance ID:DTXSID00542233
Wikidata:Q82418824
Mol file:52046-22-7.mol

Synonyms:52046-22-7;1-(4-Methylphenyl)-1H-imidazole-4-carbaldehyde;1-(p-tolyl)-1H-imidazole-4-carbaldehyde;1-(4-METHYLPHENYL)IMIDAZOLE-4-CARBALDEHYDE;SCHEMBL11765378;DTXSID00542233;TQP1179;AKOS000176554

Suppliers and Price of 1-(4-Methylphenyl)-1H-imidazole-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1-(4-methylphenyl)-1H-Imidazole-4-carboxaldehyde 97.00%
25G
$ 13300.00

AccelPharmtech
1-(4-methylphenyl)-1H-Imidazole-4-carboxaldehyde 97.00%
5G
$ 5360.00

Total 0 raw suppliers

Chemical Property of 1-(4-Methylphenyl)-1H-imidazole-4-carbaldehyde

Chemical Property:

PSA：34.89000
LogP:1.99320
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:186.079312947
Heavy Atom Count:14
Complexity:200

Purity/Quality:: 1-(4-methylphenyl)-1H-Imidazole-4-carboxaldehyde 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2C=C(N=C2)C=O

Technology Process of 1-(4-Methylphenyl)-1H-imidazole-4-carbaldehyde

There total 1 articles about 1-(4-Methylphenyl)-1H-imidazole-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52046-22-7
1-p-tolyl-1H-imidazole-4-carbaldehyde

Guidance literature:: 1-p-Tolyl-4-D-arabino-tetrahydroxybutyl-imidazol-sulfat, NaJO4, wss. Eg.;
DOI:10.1002/hlca.19600430641

Reference yield:

: 52046-22-7
1-p-tolyl-1H-imidazole-4-carbaldehyde

: 92642-74-5
1-(4-methylphenyl)4-[(hydroxyimino)methyl]-3-methylimidazolium iodide

Guidance literature:: Multi-step reaction with 2 steps

1: nitrobenzene / 216 h / Ambient temperature

2: NH₂OH / methanol / 2 h / Ambient temperature

With hydroxylamine; In methanol; nitrobenzene;
DOI:10.1021/jm00379a026

Reference yield:

: 52046-22-7
1-p-tolyl-1H-imidazole-4-carbaldehyde

: (2E,4E,6E,8E)-3,7-Dimethyl-9-(1-p-tolyl-1H-imidazol-4-yl)-nona-2,4,6,8-tetraenoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) sodium methoxide / 1.) DMF, 30 min, 2.) DMF, 1 h

2: 84 percent / LiAlH₄ / diethyl ether / 0 °C

3: Amberlist A-26, CrO₃ / tetrahydrofuran / Heating

4: 1.) sodium methoxide / 1.) DMF, 30 min, 2.) DMF, 1 h

With chromium(VI) oxide; lithium aluminium tetrahydride; Amberlist A-26; sodium methylate; In tetrahydrofuran; diethyl ether;
DOI:10.1016/0223-5234(94)90136-8