4-(MALEINIMIDO)PHENYL ISOCYANATE*

Base Information

• Chemical Name: 4-(MALEINIMIDO)PHENYL ISOCYANATE*
• CAS No.: 123457-83-0
• Molecular Formula: C11H6 N2 O3
• Molecular Weight: 214.18
• Hs Code.: 29291090
• Mol file: 123457-83-0.mol

Synonyms:4-Maleimidophenylisocyanate; N-(p-Maleimidophenyl) isocyanate; PMPI; p-Maleimidophenylisocyanate

Chemical Property of 4-(MALEINIMIDO)PHENYL ISOCYANATE*

Chemical Property:

• Vapor Pressure: 7.82E-06mmHg at 25°C
• Melting Point: 120-125 °C
• Boiling Point: 375.4°Cat760mmHg
• PKA: -1.58±0.20(Predicted)
• Flash Point: 180.8°C
• PSA: 66.81000
• Density: 1.33g/cm³
• LogP: 1.14830
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(Maleinimido)phenyl isocyanate purum,≥97.0%(CHN) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38-42
• Safety Statements: 22-36/37-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-(MALEINIMIDO)PHENYL ISOCYANATE*

There total 9 articles about 4-(MALEINIMIDO)PHENYL ISOCYANATE* which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

C15H10N4O4 → 4-(maleinimido)phenyl isocyanate (123457-83-0)

Guidance literature:

In toluene; for 7h; Reflux;

DOI:10.1002/pola.29450

Reference yield:

N-[4-(azidocarbonyl)phenyl]maleimide (58174-51-9) → 4-(maleinimido)phenyl isocyanate (123457-83-0)

Guidance literature:

In toluene; Heating;

Reference yield:

N-(4-carboxyphenyl)maleimide (17057-04-4) → 4-(maleinimido)phenyl isocyanate (123457-83-0)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / tetrahydrofuran / 2.5 h

2: NaN₃ / H₂O / 2 h / 20 °C

3: toluene / 3 h / 110 °C

With sodium azide; triethylamine; In tetrahydrofuran; water; toluene; 3: Curtius rearrangement;

DOI:10.1021/ma0496089

upstream raw materials:

N-[4-(azidocarbonyl)phenyl]maleimide

N-(4-carboxyphenyl)maleimide

N-(4-carboxyphenyl)maleamic acid

4-(2,5-dioxo-2,5-dihydro-1-pyrrol-1-yl)benzoyl chloride

Downstream raw materials:

rac-3-[6-chloro-3-(3-chloro-benzyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-piperidine-1-carboxylic acid [4-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-phenyl)-amide

C₄₀H₃₂N₄O₈

N-[p-(2-furfuryl-carbamate)phenylene]maleimide

Refernces

• 1、 Takashima, Rikito,Kida, Jumpei,Aoki, Daisuke,Otsuka, Hideyuki. "Maleimidophenyl isocyanates as postpolymerization modification agents and their applications in the synthesis of block copolymers". . p. 2396 - 2406. Retrieved 2019/08/07.
• 2、 Gǎinǎ, Viorica,Gǎinǎ, Constantin. "Ab-monomers. I: Synthesis and polymerization of furyl-maleimide monomers". . p. 881 - 890. Retrieved 2007/10/03.