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Technology Process of N5-(4-Nitrophenyl)-L-glutamine hydrochloride

N5-(4-Nitrophenyl)-L-glutamine hydrochloride

Base Information
  • Chemical Name:N5-(4-Nitrophenyl)-L-glutamine hydrochloride
  • CAS No.:67953-08-6
  • Molecular Formula:C11H14ClN3O5
  • Molecular Weight:303.70
  • Hs Code.:
  • European Community (EC) Number:267-944-5
  • UNII:7FHH4FVM3N
  • DSSTox Substance ID:DTXSID7044714
  • Wikidata:Q27268199
  • Mol file:67953-08-6.mol
N5-(4-Nitrophenyl)-L-glutamine hydrochloride

Synonyms:67953-08-6;GPNA (hydrochloride);N5-(4-Nitrophenyl)-L-glutamine hydrochloride;L-Glutamic acid gamma-(p-nitroanilide) hydrochloride;GPNA hydrochloride;UNII-7FHH4FVM3N;7FHH4FVM3N;N-(4-Nitrophenyl)-L-glutamine monohydrochloride;DTXSID7044714;L-gamma-Glutamyl-p-nitroanilide hydrochloride;L-2-Amino-4'-nitroglutaranilic acid hydrochloride;EINECS 267-944-5;L-Glutamyl-p-nitroanilide, hydrochloride;L-g-glutamyl-p-nitroanilide hydrochloride;L-Glutamic acid gamma-(p-nitroanilide), HCl;(S)-2-Amino-5-((4-nitrophenyl)amino)-5-oxopentanoic acid hydrochloride;L-gamma-Glutamyl 4-nitroanilide hydrochloride;N2-(4-Nitrophenyl)-L-glutamine hydrochloride(1:1);UNII-8ABO63DB4I;C11H13N3O5.ClH;L-Glutamine, N-(4-nitrophenyl)-, hydrochloride (1:1);C11-H13-N3-O5.Cl-H;L-Glutamic acid g-(p-nitroanilide) hydrochloride;C11H14ClN3O5;(2S)-2-amino-5-(4-nitroanilino)-5-oxopentanoic acid;hydrochloride;SCHEMBL10950909;DTXCID801333624;gamma-L-Glutamyl-p-nitroanilide HCl;Tox21_302239;MFCD00039054;s6670;AKOS040741805;GPNA (L-|A-Glutamyl-p-nitroanilide);CS-W012107;HY-W011391;L-.GAMMA-GLUTAMYL-P-NITROANILIDE;NCGC00256190-01;t-L-Glutamyl-4-nitroanilide hydrochloride;CAS-67953-08-6;D70312;G-3930;N-(4-NITROPHENYL)-L-GLUTAMINE HYDROCHLORIDE;Q27268199;L-Glutamic acid gamma-(4-nitroanilide) monohydrochloride;L-GLUTAMIC ACID .GAMMA.-(P-NITROANILIDE) HYDROCHLORIDE;(S)-2-amino-5-(4-nitrophenylamino)-5-oxopentanoic acid hydrochloride;(2S)-2-AMINO-5-((4-NITROPHENYL)AMINO)-5-OXOPENTANOIC ACID HYDROCHLORIDE;(2S)-2-AMINO-5-KETO-5-((4-NITROPHENYL)AMINO)VALERIC ACID HYDROCHLORIDE;L-Glutamic acid gamma-(p-nitroanilide) hydrochloride (H-L-Gln(Ph(4-NO2))-OH.HCl)

Suppliers and Price of N5-(4-Nitrophenyl)-L-glutamine hydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • L-Glutamic acid γ-(p-nitroanilide) hydrochloride
  • 100mg
  • $ 70.00
  • Sigma-Aldrich
  • L-Glutamic acid γ-(p-nitroanilide) hydrochloride γ-glutamyl transpeptidase substrate
  • 1g
  • $ 139.00
  • Sigma-Aldrich
  • L-Glutamic acid γ-(p-nitroanilide) hydrochloride γ-glutamyl transpeptidase substrate
  • 5g
  • $ 473.00
  • Sigma-Aldrich
  • L-Glutamic acid γ-(p-nitroanilide) hydrochloride γ-glutamyl transpeptidase substrate
  • 25g
  • $ 1640.00
  • Labseeker
  • L-GLUTAMICACIDGAMMA-(P-NITROANILIDE)HYDROCHLORIDE 95
  • 500g
  • $ 4500.00
  • CSNpharm
  • L-Glutamicacidγ-(p-nitroanilide)HCl
  • 1mg
  • $ 42.00
  • CSNpharm
  • L-Glutamicacidγ-(p-nitroanilide)HCl
  • 5mg
  • $ 105.00
  • Crysdot
  • (S)-2-Amino-5-((4-nitrophenyl)amino)-5-oxopentanoicacidhydrochloride 97%
  • 25g
  • $ 602.00
  • Chem-Impex
  • L-Glutamicacidγ-(p-nitroanilide)hydrochloride,≥99%(HPLC) ≥99%(HPLC)
  • 25G
  • $ 1502.60
  • Chem-Impex
  • L-Glutamicacidγ-(p-nitroanilide)hydrochloride,99%(HPLC) 99%(HPLC)
  • 1G
  • $ 89.60
Total 27 raw suppliers
Chemical Property of N5-(4-Nitrophenyl)-L-glutamine hydrochloride
Chemical Property:
  • Vapor Pressure:8.57E-15mmHg at 25°C 
  • Boiling Point:659.7 °C at 760 mmHg 
  • Flash Point:352.8 °C 
  • PSA：138.24000 
  • LogP:2.82390 
  • Storage Temp.:2-8°C 
  • Solubility.:Soluble in Water (up to 5 mg/ml). 
  • Hydrogen Bond Donor Count:4
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:5
  • Exact Mass:303.0621982
  • Heavy Atom Count:20
  • Complexity:347
Purity/Quality:

98%,99%, *data from raw suppliers

L-Glutamic acid γ-(p-nitroanilide) hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
  • Safety Statements: 22-24/25 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:C1=CC(=CC=C1NC(=O)CCC(C(=O)O)N)[N+](=O)[O-].Cl
  • Isomeric SMILES:C1=CC(=CC=C1NC(=O)CC[C@@H](C(=O)O)N)[N+](=O)[O-].Cl
  • Description L-γ-Glutamyl-p-nitroanilide (67953-08-6; GPNA) is a substrate for γ-glutamyl transpeptidase. GPNA is used for the determination of γ-glutamyl transpeptidase hydrolytic activity via spectrophotometric monitoring of p-nitroaniline released by the action of the enzyme on GPNA.1 GPNA has also been shown to be an inhibitor of glutamine uptake – solute-linked carrier family A1 member 5 (SLC1A5).2?Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that activates mTOR and is, thus, an interesting cancer chemotherapy target.3
  • Uses L-Glutamic acid gamma-(p-nitroanilide) is used in methods of treating cancers having a deregulated NRF2/KEAP1 pathway.
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