1H-Indole-2,3-dione, 1-[[4-(trifluoromethyl)phenyl]methyl]-

Base Information

Chemical Name:1H-Indole-2,3-dione, 1-[[4-(trifluoromethyl)phenyl]methyl]-
CAS No.:522612-12-0
Molecular Formula:C16H10F3NO2
Molecular Weight:305.256
Hs Code.:
Mol file:522612-12-0.mol

Synonyms:1-(4-Trifluoromethyl-benzyl)-1H-indole-2,3-dione;1-(4-trifluoromethylbenzyl)-1H-indole-2,3-dione;

Suppliers and Price of 1H-Indole-2,3-dione, 1-[[4-(trifluoromethyl)phenyl]methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Indole-2,3-dione, 1-[[4-(trifluoromethyl)phenyl]methyl]-

Chemical Property:

Melting Point:120 - 121 °C (toluene)
PSA：37.38000
LogP:3.49990

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Indole-2,3-dione, 1-[[4-(trifluoromethyl)phenyl]methyl]-

There total 6 articles about 1H-Indole-2,3-dione, 1-[[4-(trifluoromethyl)phenyl]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 522612-12-0
1-(4-trifluoromethylbenzyl)isatin

Guidance literature:

Reference yield: 35.0%

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 402-49-3
4-bromomethyltrifluoromethylbenzene

: 522612-12-0
1-(4-trifluoromethylbenzyl)isatin

Guidance literature:: indole-2,3-dione; With sodium hydride; In N,N-dimethyl-formamide;

4-bromomethyltrifluoromethylbenzene; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/jm030762f

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 522612-12-0
1-(4-trifluoromethylbenzyl)isatin

Guidance literature:: indole-2,3-dione; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

4-(trifluoromethyl)benzyl halide; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2015.04.062