N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline

Base Information

Chemical Name:N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline
CAS No.:134448-10-5
Molecular Formula:C₁₈H₂₉N₃O₆
Molecular Weight:383.445
Hs Code.:
DSSTox Substance ID:DTXSID10928625
Mol file:134448-10-5.mol

Synonyms:1-((S)-3-methyl-2-(((2S,3S)-3-propylcarbamoyl-oxiranecarbonyl)-amino)-pentanoyl)-pyrrolidine-2-carboxylic acid;CA 074;CA-074;N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline;nPrHN-(2S,3S)-tEps-Ile-Pro-OH

Suppliers and Price of N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
CA 074
1mg
$ 403.00

Usbiological
CA 074
1mg
$ 423.00

TRC
CA074
2.5mg
$ 580.00

Tocris
CA074 ≥98%(HPLC)
1
$ 162.00

Sigma-Aldrich
CA-074 ≥99% (TLC)
5mg
$ 422.00

ChemScene
CA-074 99.85%
1mg
$ 108.00

ChemScene
CA-074 99.85%
5mg
$ 324.00

ChemScene
CA-074 99.85%
10mg
$ 468.00

Chem-Impex
L-Trans-Epoxysuccinyl-Ile-Pro-OHpropylamide
5MG
$ 514.37

Cayman Chemical
CA-074 ≥98%
1mg
$ 143.00

Total 24 raw suppliers

Chemical Property of N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.539
Boiling Point:728.9 °C at 760 mmHg
PKA:3.43±0.20(Predicted)
Flash Point:394.7 °C
PSA：128.34000
Density:1.267 g/cm³
LogP:0.60620
Storage Temp.:−20°C
Solubility.:Soluble in methanol at 1mg/ml. Also soluble in DMSO or ethanol.
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:383.20563565
Heavy Atom Count:27
Complexity:596

Purity/Quality:

98%,99%, ^*data from raw suppliers

CA 074 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCNC(=O)C1C(O1)C(=O)NC(C(C)CC)C(=O)N2CCCC2C(=O)O
Isomeric SMILES:CCCNC(=O)[C@@H]1C(O1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N2CCC[C@H]2C(=O)O
Uses CA-074 is a potent and specific inhibitor of cathepsin B in vitro. Inhibitor of Cathepsin B.

Technology Process of N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline

There total 2 articles about N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 932385-04-1
C₂₀H₃₃N₃O₆

: 134448-10-5
N-(L-3-trans-n-propylcarbamoyloxirane-2-carbonyl)-L-isoleucyl-L-proline

Guidance literature:: C₂₀H₃₃N₃O₆; With lithium hydroxide; water; In tetrahydrofuran; for 5h;

With potassium hydrogensulfate; In tetrahydrofuran; water; pH=2;