1-Azabicyclo[2.2.2]octane-2-carboxylic acid

Base Information

Chemical Name:1-Azabicyclo[2.2.2]octane-2-carboxylic acid
CAS No.:52601-24-8
Molecular Formula:C₈H₁₃NO₂
Molecular Weight:155.197
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70480916
Nikkaji Number:J2.567.251H
Mol file:52601-24-8.mol

Synonyms:QUINUCLIDINE-2-CARBOXYLIC ACID;52601-24-8;1-AZABICYCLO[2.2.2]OCTANE-2-CARBOXYLIC ACID;(R)-quinuclidine-2-carboxylic acid;1-Azabicyclo[2.2.2]octane-2-carboxylic acid, (2R)-;SCHEMBL572684;DTXSID70480916;D-Threoninemethylesterhydrochloride;LIUAALCHBQSCCX-UHFFFAOYSA-N;CCA60124;QUINUCLIDINE-2-CARBOXYLICACID;AKOS006311027;racemic 2-quinuclidine carboxylic acid;AB87002;AB92113;CS-0453259;A913552

Suppliers and Price of 1-Azabicyclo[2.2.2]octane-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Quinuclidine-2-carboxylicacid 95+%
1g
$ 1020.00

Chemenu
Quinuclidine-2-carboxylicacid 95%
1g
$ 961.00

ACHEMBLOCK
1-azabicyclo[2.2.2]octane-2-carboxylicacid 97%
5G
$ 1650.00

AccelPharmtech
1-Azabicyclo[2.2.2]octane-2-carboxylicacid 97.00%
25G
$ 7320.00

AccelPharmtech
1-Azabicyclo[2.2.2]octane-2-carboxylicacid 97.00%
5G
$ 3900.00

AccelPharmtech
1-Azabicyclo[2.2.2]octane-2-carboxylicacid 97.00%
1G
$ 2280.00

Total 5 raw suppliers

Chemical Property of 1-Azabicyclo[2.2.2]octane-2-carboxylic acid

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Boiling Point:284.486oC at 760 mmHg
PKA:2.45±0.20(Predicted)
Flash Point:125.853oC
PSA：40.54000
Density:1.231g/cm3
LogP:0.49320
XLogP3:-1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:155.094628657
Heavy Atom Count:11
Complexity:173

Purity/Quality:

97% ^*data from raw suppliers

Quinuclidine-2-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CCC1CC2C(=O)O

Technology Process of 1-Azabicyclo[2.2.2]octane-2-carboxylic acid

There total 8 articles about 1-Azabicyclo[2.2.2]octane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52601-24-8,757899-36-8
1-azabicyclo[2.2.2]octane-2-carboxylic acid

Guidance literature:: With sodium hydroxide;
DOI:10.1002/hlca.19540370723

Reference yield:

: 40500-10-5
3-(tetrahydro-2H-pyran-4-yl)propanoic acid

: 52601-24-8,757899-36-8
1-azabicyclo[2.2.2]octane-2-carboxylic acid

Guidance literature:: With hydrogen bromide; Erwaermen des Reaktionsprodukts mit Brom und rotem Phosphor, Erwaermen des Reaktionsgemisches mit Aethanol und Erhitzen des Reaktionsprodukts mit NH₃ in Methanol bei 135grad;

Reference yield:

: 52601-24-8,757899-36-8
1-azabicyclo[2.2.2]octane-2-carboxylic acid

Guidance literature:: With hydrogenchloride; diethyl ether; Erwaermen des Reaktionsprodukts in CHCl₃ mit SOCl₂, Erwaermen des Reaktionsprodukts mit Pyridin und Erwaermen des Reaktionsprodukts mit wss. HCl;