2-(4-Hydroxyphenyl)benzofuran-6-ol

Base Information

Chemical Name:2-(4-Hydroxyphenyl)benzofuran-6-ol
CAS No.:52814-74-1
Molecular Formula:C14H10O3
Molecular Weight:226.232
Hs Code.:
DSSTox Substance ID:DTXSID30356062
Nikkaji Number:J445.667J
Wikidata:Q82135199
Pharos Ligand ID:JG2UXDPW2W2Y
ChEMBL ID:CHEMBL265940

Synonyms:2-(4-hydroxyphenyl)benzofuran-6-ol;52814-74-1;2-(4-hydroxyphenyl)-1-benzofuran-6-ol;6-Benzofuranol, 2-(4-hydroxyphenyl)-;CHEMBL265940;ZINC 00334865;SCHEMBL9138143;DTXSID30356062;BDBM50423498

Suppliers and Price of 2-(4-Hydroxyphenyl)benzofuran-6-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(4-Hydroxyphenyl)benzofuran-6-ol

Chemical Property:

Melting Point:243-244 °C
Boiling Point:303.0±11.0 °C(Predicted)
PSA：53.60000
Density:1.342±0.06 g/cm3(Predicted)
LogP:3.51100
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:226.062994177
Heavy Atom Count:17
Complexity:260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC3=C(O2)C=C(C=C3)O)O

Technology Process of 2-(4-Hydroxyphenyl)benzofuran-6-ol

There total 5 articles about 2-(4-Hydroxyphenyl)benzofuran-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 52814-74-1
2-(4-hydroxyphenyl)-6-hydroxybenzofuran

Guidance literature:: With titanium tetrachloride; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield: 65.0%

: 860184-70-9
6-(benzyloxy)-2-(4-benzyloxyphenyl)benzofuran

: 52814-74-1
2-(4-hydroxyphenyl)-6-hydroxybenzofuran

Guidance literature:: With titanium tetrachloride; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1007/s00044-016-1694-8

Reference yield:

: 52085-14-0
4-benzoxy-salicylaldehyde

: 52814-74-1
2-(4-hydroxyphenyl)-6-hydroxybenzofuran

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; sodium iodide; butanone / Behandeln des Reaktionsprodukts mit aethanol. Kalilauge und Erhitzen des danach isolierten Reaktionsprodukts in Chinolin auf 180grad

2: aqueous hydrochloric acid; acetic acid

With hydrogenchloride; potassium carbonate; acetic acid; butanone; sodium iodide;