1-Pentyn-3-one, 4-methyl-1-(trimethylsilyl)-

Base Information

Chemical Name:1-Pentyn-3-one, 4-methyl-1-(trimethylsilyl)-
CAS No.:53210-05-2
Molecular Formula:C9H16OSi
Molecular Weight:168.311
Hs Code.:
DSSTox Substance ID:DTXSID70455725
Wikidata:Q82277837

Synonyms:53210-05-2;1-Pentyn-3-one, 4-methyl-1-(trimethylsilyl)-;SCHEMBL3685563;DTXSID70455725

Suppliers and Price of 1-Pentyn-3-one, 4-methyl-1-(trimethylsilyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-Pentyn-3-one, 4-methyl-1-(trimethylsilyl)-

Chemical Property:

Boiling Point:73 °C(Press: 12 Torr)
PSA：17.07000
Density:0.869±0.06 g/cm3(Predicted)
LogP:2.09230
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:168.097041664
Heavy Atom Count:11
Complexity:209

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(=O)C#C[Si](C)(C)C

Technology Process of 1-Pentyn-3-one, 4-methyl-1-(trimethylsilyl)-

There total 1 articles about 1-Pentyn-3-one, 4-methyl-1-(trimethylsilyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 81353-38-0
(trimethylsilylethynyl)tributyltin

: 79-30-1
isobutyryl chloride

: 53210-05-2
4-methyl-1-(trimethylsilyl)pent-1-yn-3-one

Guidance literature:: bis-triphenylphosphine-palladium(II) chloride; In 1,2-dichloro-ethane; at 84 ℃; for 2h;
DOI:10.1021/jo00134a010

Reference yield: 83.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 53210-05-2
4-methyl-1-(trimethylsilyl)pent-1-yn-3-one

: 71451-04-2
1-<(trimethylsilyl)ethynyl>-2,2-dimethylethenyl triflate

Guidance literature:: With 2,6-di-tert-butyl-4-methylpyridine; In dichloromethane; at 20 ℃;
DOI:10.1002/(SICI)1521-3773(19990712)38:13/14<1940::AID-ANIE1940>3.0.CO;2-8

Reference yield:

: 53210-05-2
4-methyl-1-(trimethylsilyl)pent-1-yn-3-one

: 244191-30-8
C₄₄H₅₆Si₂

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / 2,6-tBu₂-4-CH₃-C₅H₂NH₂ / CH₂Cl₂ / 20 °C

2: Et₂NH; CuI / Pd(PPh₃)4 / dimethylformamide; methanol; tetrahydrofuran / 2.5 h / 20 °C

With copper(l) iodide; 2,6-di-tert-butyl-4-methylpyridine; diethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; 1: Substitution / 2: Substitution;
DOI:10.1002/(SICI)1521-3773(19990712)38:13/14<1940::AID-ANIE1940>3.0.CO;2-8