Dimethyl (3-cyclohexyl-2-oxopropyl)phosphonate

Base Information

Chemical Name:Dimethyl (3-cyclohexyl-2-oxopropyl)phosphonate
CAS No.:53273-28-2
Molecular Formula:C11H21O4P
Molecular Weight:248.259
Hs Code.:
DSSTox Substance ID:DTXSID70558720
Wikidata:Q82441110
Mol file:53273-28-2.mol

Synonyms:53273-28-2;Dimethyl (3-cyclohexyl-2-oxopropyl)phosphonate;Phosphonic acid, (3-cyclohexyl-2-oxopropyl)-, dimethyl ester;Dimethyl 2-oxo-3-cyclohexylpropylphosphonate;1-cyclohexyl-3-dimethoxyphosphorylpropan-2-one;SCHEMBL4942103;DTXSID70558720;MFCD25964258;AKOS030255424;dimethyl 3-cyclohexyl-2-oxopropylphosphonate;(3-Cyclohexyl-2-oxopropyl)-phosphonic acid dimethyl ester, 98%

Suppliers and Price of Dimethyl (3-cyclohexyl-2-oxopropyl)phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Dimethyl (3-cyclohexyl-2-oxopropyl)phosphonate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:248.11774614
Heavy Atom Count:16
Complexity:263

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COP(=O)(CC(=O)CC1CCCCC1)OC

Technology Process of Dimethyl (3-cyclohexyl-2-oxopropyl)phosphonate

There total 3 articles about Dimethyl (3-cyclohexyl-2-oxopropyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 14352-61-5
methyl cyclohexylacetate

: 756-79-6
dimethyl methane phosphonate

: 53273-28-2
dimethyl 2-oxo-3-cyclohexylpropylphosphonate

Guidance literature:: dimethyl methane phosphonate; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

methyl cyclohexylacetate; In tetrahydrofuran; at -78 - 0 ℃; for 1.5h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.9b00662

Reference yield: 70.0%

: 53273-28-2
dimethyl 2-oxo-3-cyclohexylpropylphosphonate

Guidance literature:

Reference yield:

: 4202-14-6
dimethyl (2-oxopropyl)phosphonate

: 53273-28-2
dimethyl 2-oxo-3-cyclohexylpropylphosphonate

Guidance literature:: dimethyl (2-oxopropyl)phosphonate; With sodium hydride;

With n-butyllithium;

c-Hex-CH₂-X;
DOI:10.1016/j.bmcl.2004.01.063