7-chloro-1-methyl-5-(o-tolyl)-1H-benzo[e][1,4]diazepin-2(3H)-one

Base Information

Chemical Name:7-chloro-1-methyl-5-(o-tolyl)-1H-benzo[e][1,4]diazepin-2(3H)-one
CAS No.:5358-34-9
Molecular Formula:C17H15ClN2O
Molecular Weight:298.772
Hs Code.:
DSSTox Substance ID:DTXSID80878123
Nikkaji Number:J1.586.265C
Mol file:5358-34-9.mol

Synonyms:5358-34-9;DTXSID80878123;1,4-BENZDAZEPIN-2-ON-1-ME-5-(2ME-PH)7-CL;7-chloro-1-methyl-5-(o-tolyl)-1H-benzo[e][1,4]diazepin-2(3H)-one;7-Chloro-1,3-dihydro-1-methyl-5-(2-methylphenyl)-2H-1,4-benzodiazepine-2-one

Suppliers and Price of 7-chloro-1-methyl-5-(o-tolyl)-1H-benzo[e][1,4]diazepin-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-chloro-1-methyl-5-(o-tolyl)-1H-benzo[e][1,4]diazepin-2(3H)-one

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:298.0872908
Heavy Atom Count:21
Complexity:437

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C2=NCC(=O)N(C3=C2C=C(C=C3)Cl)C

Technology Process of 7-chloro-1-methyl-5-(o-tolyl)-1H-benzo[e][1,4]diazepin-2(3H)-one

There total 3 articles about 7-chloro-1-methyl-5-(o-tolyl)-1H-benzo[e][1,4]diazepin-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 439-14-5
diazepam

: potassium trifluoro(methyl)boranuide

: C₁₈H₁₇ClN₂O

: 5358-34-9
7-chloro-1-methyl-5-o-tolyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

Guidance literature:: With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium fluoride; In water; butan-1-ol; at 100 ℃; for 18h; Electrolysis;
DOI:10.1002/chem.202103837

Reference yield: 31.0%

: 823-96-1
Trimethylboroxine

: 439-14-5
diazepam

: C₁₈H₁₇ClN₂O

: 5358-34-9
7-chloro-1-methyl-5-o-tolyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

Guidance literature:: With pentamethylcyclopentadienyl(benzene)cobalt(III) hexafluorophosphate; potassium carbonate; silver carbonate; In 2-methyltetrahydrofuran; at 60 ℃; for 16h; Inert atmosphere; Sealed tube;
DOI:10.1038/s41557-020-0475-7