2,2-Dibromo-1-methylcyclopropanecarbonyl chloride

Base Information

• Chemical Name: 2,2-Dibromo-1-methylcyclopropanecarbonyl chloride
• CAS No.: 5365-22-0
• Molecular Formula: C₅H₅Br₂ClO
• Molecular Weight: 276.355
• Hs Code.: 2916209090
• DSSTox Substance ID: DTXSID001234262
• Nikkaji Number: J2.210.504C
• Mol file: 5365-22-0.mol

Synonyms:2,2-DIBROMO-1-METHYLCYCLOPROPANECARBONYL CHLORIDE;5365-22-0;2,2-dibromo-1-methylcyclopropane-1-carbonyl chloride;SCHEMBL11819217;DTXSID001234262;MFCD00760271;AKOS005173292;VS-04648

Chemical Property of 2,2-Dibromo-1-methylcyclopropanecarbonyl chloride

Chemical Property:

• PSA: 17.07000
• LogP: 2.64790
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 275.83752
• Heavy Atom Count: 9
• Complexity: 168

Purity/Quality:

98%min ^*data from raw suppliers

2,2-Dibromo-1-methylcyclopropanecarbonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CC1(Br)Br)C(=O)Cl

Technology Process of 2,2-Dibromo-1-methylcyclopropanecarbonyl chloride

There total 3 articles about 2,2-Dibromo-1-methylcyclopropanecarbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dibromo-1-methylcyclopropanecarboxylic acid (5365-21-9) → 2,2-Dibromo-1-methylcyclopropanecarbonyl chloride (5365-22-0)

Guidance literature:

With thionyl chloride; In benzene; for 4h; Heating;

Reference yield:

2,2-dibromo-1-methylcyclopropane-1-methanol (64670-28-6) → 2,2-Dibromo-1-methylcyclopropanecarbonyl chloride (5365-22-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / Jones' reagent

2: SOCl₂, DMF / toluene / Heating

With thionyl chloride; jones' reagent; N,N-dimethyl-formamide; In toluene;

DOI:10.1039/P19960002157

Reference yield:

→ 2,2-Dibromo-1-methylcyclopropanecarbonyl chloride (5365-22-0)

Guidance literature:

Carbonsaeure 7, Thionylchlorid;

upstream raw materials:

2,2-dibromo-1-methylcyclopropanecarboxylic acid

2,2-dibromo-1-methylcyclopropane-1-methanol

Downstream raw materials:

(2,2-Dibromo-1-methyl-cyclopropyl)-p-tolyl-methanone

α(RS)-cyano-3-phenoxybenzyl 2,2-dibromo-1-methylcyclopropane-1-carboxylate

3-phenoxybenzyl 2,2-dibromo-1-methylcyclopropane-1-carboxylate