4-Azido-2-nitro-L-phenylalanine

Base Information

Chemical Name:4-Azido-2-nitro-L-phenylalanine
CAS No.:53807-56-0
Molecular Formula:C₉H₉N₅O₄
Molecular Weight:251.202
Hs Code.:
DSSTox Substance ID:DTXSID70707655
Mol file:53807-56-0.mol

Synonyms:4-Azido-2-nitro-L-phenylalanine;53807-56-0;2-nitro-4-azido-phenylalanine;DTXSID70707655

Suppliers and Price of 4-Azido-2-nitro-L-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Azido-2-nitro-L-phenylalanine

Chemical Property:

XLogP3:-0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:251.06545379
Heavy Atom Count:18
Complexity:376

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1N=[N+]=[N-])[N+](=O)[O-])CC(C(=O)O)N
Isomeric SMILES:C1=CC(=C(C=C1N=[N+]=[N-])[N+](=O)[O-])C[C@@H](C(=O)O)N

Technology Process of 4-Azido-2-nitro-L-phenylalanine

There total 2 articles about 4-Azido-2-nitro-L-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57213-14-6
4-amino-2-nitro-L-phenylalanine

: 53807-56-0
p-Azido-o-nitrophenylalanin

Guidance literature:: Multistep reaction; (i) NaNO₂, aq. HCl, (ii) NaN₃;
DOI:10.1002/hlca.19750580524

Reference yield:

: 943-80-6
4-amino-L-phenylalanine

: 53807-56-0
p-Azido-o-nitrophenylalanin

Guidance literature:: Multi-step reaction with 2 steps

1: HNO₃, H₂SO₄

2: (i) NaNO₂, aq. HCl, (ii) NaN₃

With sulfuric acid; nitric acid;
DOI:10.1002/hlca.19750580524

Reference yield:

: 53807-56-0
p-Azido-o-nitrophenylalanin

: 6-(dimethylamino)-9-<3'-<(4-azido-2-nitro-L-phenylalanyl)amino>-3'-deoxy-β-D-ribofuranosyl>purine

Guidance literature:: Multi-step reaction with 3 steps

1: 0.5 N aq. NaOH / dioxane / 1 h / Ambient temperature

2: 77 percent / N-(ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline (EEDQ) / aq. ethanol; CHCl₃ / 4 h / 45 °C

3: 36 percent / trifluoroacetic acid / 0.22 h / Ambient temperature

With sodium hydroxide; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; trifluoroacetic acid; In 1,4-dioxane; ethanol; chloroform;
DOI:10.1021/jm00135a013