2-Aminopropiophenone hydrochloride

Base Information

Chemical Name:2-Aminopropiophenone hydrochloride
CAS No.:16735-19-6
Molecular Formula:C9H11 N O . Cl H
Molecular Weight:185.653
Hs Code.:2939800000
NSC Number:166465
DSSTox Substance ID:DTXSID201347679
Mol file:16735-19-6.mol

Synonyms:2-Aminopropiophenone hydrochloride;16735-19-6;Aminopropiophenone hydrochloride;2-amino-1-phenylpropan-1-one;hydrochloride;NSC 166465;Propiophenone, 2-amino-, hydrochloride;1-Propanone, 2-amino-1-phenyl-, hydrochloride;rac-Cathinone Hydrochloride;DL-Cathinone hydrochloride;SCHEMBL1567990;2-AMINOPROPIOPHENONE HCL;DTXSID201347679;NSC166465;AKOS026672026;NSC-166465;LS-125041;F13376;1-Propanone, 1-(2-aminophenyl)-, hydrochloride (1:1);rac-Cathinone Hydrochloride 1.0 mg/ml in Methanol (as free base)

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of 2-Aminopropiophenone hydrochloride

Chemical Property:

Vapor Pressure:0.0167mmHg at 25°C
Melting Point:185-189 °C
Boiling Point:255°Cat760mmHg
Flash Point:108°C
PSA：43.09000
Density:1.054g/cm³
LogP:2.71880
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:185.0607417
Heavy Atom Count:12
Complexity:139

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C1=CC=CC=C1)N.Cl
Description Cathinone, the main psychoactive alkaloid from the khat plant (C. edulis), is a potent central stimulant and a naturally occurring analog of amphetamine. Cathinone, the main psychoactive alkaloid from the khat plant (C. edulis), is a potent central stimulant and a naturally occurring analog of amphetamine. DL-Cathinone is a racemic mixture of (?)-(S)-cathinone and its less potent (+)-isomer. Like amphetamine, DL-cathinone and (?)-(S)-cathinone are potent releasers of norepinephrine and dopamine. With an ED50 value of 0.24 mg/kg, DL-cathinone produces amphetamine-like effects on the operant behavior of rats trained to discriminate 0.2-0.8 mg/kg of (D)-amphetamine. This product is intended for research and forensic applications. Cathinone, the main psychoactive alkaloid from the khat plant (C. edulis), is a potent central stimulant and a naturally occurring analog of amphetamine. DL-Cathinone is a racemic mixture of (?)-(S)-cathinone and its less potent (+)-isomer. Like amphetamine, DL-cathinone and (?)-(S)-cathinone are potent releasers of norepinephrine and dopamine. With an ED50 value of 0.24 mg/kg, DL-cathinone produces amphetamine-like effects on the operant behavior of rats trained to discriminate 0.2-0.8 mg/kg of (D)-amphetamine. This product is intended for research and forensic applications.
Uses Racemic Cathinone (C225700), a psychoactive alkaloid found in the leaves of the khat plant. Cathinone is chemically similar to ephedrine and amphetamines and is known to exhibit antidepressant propert ies.

Technology Process of 2-Aminopropiophenone hydrochloride

There total 14 articles about 2-Aminopropiophenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 16735-27-6
2,2,2-trifluoro-N-(1-oxo-1-phenylpropaN-2-yl)acetamide

: 16735-19-6
2-amino-1-phenylpropan-1-one hydrochloride

Guidance literature:: With hydrogenchloride; In isopropyl alcohol;
DOI:10.1016/j.bmc.2004.05.033

Reference yield: 79.0%

: 2114-00-3
2-bromo-1-phenyl-1-propanone

: 16735-19-6
2-amino-1-phenylpropan-1-one hydrochloride

Guidance literature:: 2-bromo-1-phenyl-1-propanone; With sodium diformamide; In acetonitrile; at 75 ℃; for 8h;

With hydrogenchloride; In water; for 1h; Reflux;
DOI:10.1002/adsc.202000171