Thr-Glu

Base Information

• Chemical Name: Thr-Glu
• CAS No.: 54532-73-9
• Molecular Formula: C9H16N2O6
• Molecular Weight: 248.23300
• Nikkaji Number: J1.912.513K
• Wikidata: Q27144966
• Metabolomics Workbench ID: 78982
• Mol file: 54532-73-9.mol

Synonyms:Thr-Glu;H-Thr-Glu-OH;threonylglutamic acid;L-threonyl-L-glutamic acid;TE dipeptide;T-E Dipeptide;Threoninylglutamate;Threoninyl-Glutamate;L-Thr-L-Glu;Threonyl-glutamic acid;L-Threoninyl-L-Glutamate;Threonine Glutamate dipeptide;Threonine-Glutamate dipeptide;SCHEMBL10804597;CHEBI:74857;N-(L-threonyl)-L-glutamic acid;BECPPKYKPSRKCP-ZDLURKLDSA-N;HY-P4619;MFCD00238182;CS-0655415;Q27144966;(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]pentanedioic acid

Chemical Property of Thr-Glu

Chemical Property:

• PSA: 149.95000
• LogP: -0.78010
• Storage Temp.: -15°C
• XLogP3: -4.5
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 7
• Exact Mass: 248.10083623
• Heavy Atom Count: 17
• Complexity: 306

Purity/Quality:

99%+, ^*data from raw suppliers

H-THR-GLU-OH 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C(C(=O)NC(CCC(=O)O)C(=O)O)N)O
• Isomeric SMILES: C[C@H]([C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N)O

Technology Process of Thr-Glu

There total 1 articles about Thr-Glu which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) + 2-(p-biphenylyl)-2-propyloxycarbonyl-Thr-OH (47503-88-8) → MAP Kinase ERK2 [182-184] + H-Thr-Glu-OH (54532-73-9)

Guidance literature:

Multistep reaction.;

DOI:10.1039/b617699m

upstream raw materials:

N-tert-butoxycarbonyl-L-leucine

2-(p-biphenylyl)-2-propyloxycarbonyl-Thr-OH

Refernces