1,2,3-Triphenyl-1H-indole

Base Information

• Chemical Name: 1,2,3-Triphenyl-1H-indole
• CAS No.: 54879-94-6
• Molecular Formula: C26H19N
• Molecular Weight: 345.444
• DSSTox Substance ID: DTXSID50366921
• Nikkaji Number: J1.805.070F
• Wikidata: Q82152402
• Mol file: 54879-94-6.mol

Synonyms:1,2,3-Triphenyl-1H-indole;54879-94-6;1H-Indole, 1,2,3-triphenyl-;Oprea1_121171;Oprea1_444814;DTXSID50366921;NCGC00321512-01;AB01316928-02

Chemical Property of 1,2,3-Triphenyl-1H-indole

Chemical Property:

• XLogP3: 6.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 345.151749610
• Heavy Atom Count: 27
• Complexity: 455

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=C(N(C3=CC=CC=C32)C4=CC=CC=C4)C5=CC=CC=C5

Technology Process of 1,2,3-Triphenyl-1H-indole

There total 21 articles about 1,2,3-Triphenyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

diphenyl acetylene (501-65-5) + N-phenyl isatoic anhydride (20877-86-5) → N-phenyl-2,3-diphenylindole (54879-94-6)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; In toluene; at 20 - 160 ℃; for 12h; under 760.051 Torr; Inert atmosphere;

DOI:10.1246/cl.130578

Reference yield: 92.0%

2-isobutylidene-1,1-diphenylhydrazine (861593-95-5) + diphenyl acetylene (501-65-5) → N-phenyl-2,3-diphenylindole (54879-94-6)

Guidance literature:

With 1,2,3,4-tetraphenylcyclopentadiene; tris(acetonitrile)pentamethylcyclopentadienylrhodium(III) hexafluoroantimonate; copper diacetate; In N,N-dimethyl-formamide; at 120 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.04.016

Reference yield: 90.0%

diphenyl acetylene (501-65-5) + 1,1-Diphenylhydrazine (530-50-7) → N-phenyl-2,3-diphenylindole (54879-94-6)

Guidance literature:

Ti(dap)2(NMe₂)2; In toluene; at 100 ℃; for 48h;

DOI:10.1021/ol0201052

upstream raw materials:

2-hydroxy-2-phenylacetophenone

diphenylamine

(E)-3-Ureido-but-2-enoic acid ethyl ester

N-phenylamino-1 triphenyl-1,2,2 ethylene

Downstream raw materials:

N-(2-benzoylphenyl)benzamide

9-phenyl-9H-dibenzocarbazole

2,3-diphenyl-1H-indole